178675-17-7

Upstream product

• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 
• 532-55-8 Benzoyl isothiocyanate 
• 1147550-11-5 ammonium thiocyanate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1312701-30-6 (E)-2-(2-benzylidenehydrazinyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1312701-31-7 (E)-2-(2-(4-chlorobenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1312701-32-8 (E)-2-(2-(4-methoxybenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1312701-33-9 (E)-2-(2-(4-bromobenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1312701-34-0 (E)-2-(2-(4-methylbenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1312701-35-1 (E)-2-(2-(3-chlorobenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1312701-36-2 (E)-2-(2-(3-bromobenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1312701-37-3 (E)-2-(2-(3-methylbenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 1312701-46-4 1-phenylthieno[2,3-e][1,2,4]triazolo[4,3-a]pyrimidin-5(4H)-one 
• 1312701-47-5 1-(4-chlorophenyl)thieno[2,3-e][1,2,4]triazolo[4,3-a]pyramidin-5(4H)-one 
• 1312701-48-6 1-(4-methoxyphenyl)thieno[2,3-e][1,2,4]triazolo[4,3-a]pyramidin-5(4H)-one 
• 1312701-49-7 1-(4-bromophenyl)thieno[2,3-e][1,2,4]triazolo[4,3-a]pyramidin-5(4H)-one 
• 1312701-50-0 1-p-tolylthieno[2,3-e][1,2,4]triazolo[4,3-a]pyramidin-5(4H)-one 
• 1312701-51-1 1-(3-chlorophenyl)thieno[2,3-e][1,2,4]triazolo[4,3-a]pyramidin-5(4H)-one 

Relevant academic research and scientific papers

NOVEL PROCESS FOR PREPARING NOVEL THIOXO THIENOPYRIMIDINONE DERIVATIVES AND INTERMEDIATES USED THEREIN

The present invention relates to a preparation method of 2-thioxo thienopyrimidin-4-one represented by chemical formula 1, and an intermediate product used thereto. The preparation method of the present invention comprises the steps of: having a reaction

Synthesis of new 1-phenylthieno[1,2,4]triazolo[4,3-a]pyrimidin-5(4H)-one derivatives

A series of novel 1-phenylthieno[1,2,4]triazolo[4,3-a]pyrimidin-5(4H)-one derivatives 5 and 6 were synthesized by oxidative cyclization of thienopyrimidinonyl hydrazones using iodobenzene diacetate.

PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM

The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides compounds represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C1-C6 alkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.

Novel heterocycles derived from substituted aroylthioureas: Synthesis of 3,1-benzothiazin-4-ones, thieno[3,2-d][1,3]thiazin-4-ones and 1,2,4-thiadiazolo[2,3-a][3,1]benzothiazin-5-ones

A series of heterocyclic aroylthioureas has been prepared and investigated as starting materials for ring closure reactions. The formation of several new 3,1-benzothiazin-4-ones and thieno[3,2-d][1,3]thiazin-4-ones (via cyclocondensation reactions) is rep