- POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND
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Provided is a polymer film containing at least one of a compound represented by formula (1) of hydrates, solvates, or salts thereof. Y is a methine group or nitrogen atom. Qa, Qb, and Qc are a single bond or a divalent linking group. Ra, Rb, and Rc, are hydrogen atom, alkyl group, alkenyl group, alkynyl group, aryl group, cyano group, halogen group, or heterocyclic group. X2 is a single bond or a divalent linking group. X1 is a single bond or a predetermined divalent linking group. R1 and R2 are a hydrogen atom, alkyl group, alkenyl group, alkynyl group, aryl group, or heterocyclic group Formula (1)
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Paragraph 0361-0365
(2016/06/28)
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- Lewis acid-catalyzed synthesis of 4-aminopyrimidines: A scalable industrial process
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Pyrimidine synthesis starting from acrylonitrile has been known since the 1960s. The new Lewis acid-catalyzed condensation reaction allows the synthesis of 4-aminopyrimidines starting from the easily accessible chemical acrylonitrile without the need for carcinogenic chemicals and costly derivatization in up to 90% yield. The method is versatile and applicable for industrial-scale synthesis of biologically relevant substances such as vitamin B1 and trimethoprim.
- Letinois, Ulla,Schuetz, Jan,Haerter, Ralph,Stoll, Rinke,Huffschmidt, Florian,Bonrath, Werner,Karge, Reinhard
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supporting information
p. 427 - 431
(2013/05/09)
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- Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis
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The search for effective therapeutics for cryptosporidiosis and toxoplasmosis has led to the discovery of novel inhibitors of dihydrofolate reductase (DHFR) that possess high ligand efficiency: compounds with high potency and low molecular weight. Detaile
- Pelphrey, Phillip M.,Popov, Veljko M.,Joska, Tammy M.,Beierlein, Jennifer M.,Bolstad, Erin S. D.,Fillingham, Yale A.,Wright, Dennis L.,Anderson, Amy C.
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p. 940 - 950
(2007/10/03)
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- 5[W(substituted aryl)alkenylene and alkynylene]-2,4-diaminopyrimidines as pesticides
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5-Substituted-2,4-diaminopyrimidines, and agriculturally acceptable salts thereof, when present in insecticidally or acaricidally effective amounts, and with a suitable agricultural carrier, are useful as active ingredients in novel insecticidal and acaricidal compositions. These pyrimidines may be represented by the following formula: STR1 wherein Ar is STR2 and wherein U is an alkenylene or alkynylene moiety, and R, R1, R2, R3, R4, V, W, X, Y, Z and n are as defined herein; also disclosed and claimed are novel intermediates thereof.
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- Insecticidal 5-substituted-2,4-diaminopyrimidine derivatives
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An insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a compound of the formula: STR1 wherein R, R1, R2, R3, R7, R8, m, n, and p are as defined herein, and agriculturally acceptable salts thereof, and methods of using the same.
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- Pyrimidine N-Oxides. VI. The Ionization Constants of Pyrimidine-2,4-diamine N-Oxides
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The ionization constants of some pyrimidine-2,4-diamines and their N-oxides, including the drugs 'trimethoprim' and 'minoxidil', are reported.The syntheses of several pyrimidine-2,4-diamine N-oxides are described.
- Cowden, William B.,Jacobsen, Noel W.
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p. 1195 - 1201
(2007/10/02)
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- 2,4-Diamino-6-methyl-5-(halophenylazo) pyrimidines
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Compounds comprising selected 2,4-diamino-6-methyl-5-(halophenylazo) pyrimidines which are highly active as folic acid antagonists. The compounds include 2,4-diamino-6-methyl-5-(m-chlorophenylazo) pyrimidine; 2,4-diamino-6-methyl-5-(p-bromophenylazo) pyri
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