1791-73-7

Usage

Uses

Used in Pharmaceutical Synthesis:
2,4-Pyrimidinediamine, 6-methyl(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to form complex molecular structures that can exhibit therapeutic effects.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, 2,4-Pyrimidinediamine, 6-methyl(9CI) serves as a building block for the creation of diverse organic compounds, contributing to the development of new materials and chemical entities.
Used in Medicinal Chemistry Research:
2,4-Pyrimidinediamine, 6-methyl(9CI) is utilized in medicinal chemistry for the exploration of its potential as a therapeutic agent or a component in drug design, given its unique structural features and reactivity.

InChI:InChI=1/C5H8N4/c1-3-2-4(6)9-5(7)8-3/h2H,1H3,(H4,6,7,8,9)

Upstream product

• 3438-46-8 4-Methylpyrimidine 
• 5424-21-5 2,4-dichloro-6-methylpyrimidine 
• 5600-21-5 2-amino-6-methyl-4-chloropyrimidine 
• 7664-41-7 ammonia 
• 50-01-1 guanidine hydrochloride 
• 70807-22-6 3-hydroxycrotononitrile sodium salt 
• 1118-61-2 3-Aminocrotononitrile 

Downstream Products

• 34289-21-9 6-methyl-5-phenylazo-pyrimidine-2,4-diamine 
• 2829-59-6 6-methyl-2,4-diamino-5-nitropyrimidine 
• 91481-95-7 6-methylpyrimidine-2,4-diamine 3-oxide 
• 15640-40-1 bis(4-hydroxy-2,6-dimethoxyphenyl)methane 
• 42399-22-4 5-hydroxy-6-methyl-2,4-diaminopyrimidine 
• 189810-94-4 2,4-diamino-5-iodo-6-methylpyrimidine 

Relevant academic research and scientific papers

POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND

Provided is a polymer film containing at least one of a compound represented by formula (1) of hydrates, solvates, or salts thereof. Y is a methine group or nitrogen atom. Qa, Qb, and Qc are a single bond or a divalent linking group. Ra, Rb, and Rc, are hydrogen atom, alkyl group, alkenyl group, alkynyl group, aryl group, cyano group, halogen group, or heterocyclic group. X2 is a single bond or a divalent linking group. X1 is a single bond or a predetermined divalent linking group. R1 and R2 are a hydrogen atom, alkyl group, alkenyl group, alkynyl group, aryl group, or heterocyclic group Formula (1)

Lewis acid-catalyzed synthesis of 4-aminopyrimidines: A scalable industrial process

Pyrimidine synthesis starting from acrylonitrile has been known since the 1960s. The new Lewis acid-catalyzed condensation reaction allows the synthesis of 4-aminopyrimidines starting from the easily accessible chemical acrylonitrile without the need for carcinogenic chemicals and costly derivatization in up to 90% yield. The method is versatile and applicable for industrial-scale synthesis of biologically relevant substances such as vitamin B1 and trimethoprim.

Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis

The search for effective therapeutics for cryptosporidiosis and toxoplasmosis has led to the discovery of novel inhibitors of dihydrofolate reductase (DHFR) that possess high ligand efficiency: compounds with high potency and low molecular weight. Detaile

5[W(substituted aryl)alkenylene and alkynylene]-2,4-diaminopyrimidines as pesticides

5-Substituted-2,4-diaminopyrimidines, and agriculturally acceptable salts thereof, when present in insecticidally or acaricidally effective amounts, and with a suitable agricultural carrier, are useful as active ingredients in novel insecticidal and acaricidal compositions. These pyrimidines may be represented by the following formula: STR1 wherein Ar is STR2 and wherein U is an alkenylene or alkynylene moiety, and R, R1, R2, R3, R4, V, W, X, Y, Z and n are as defined herein; also disclosed and claimed are novel intermediates thereof.

Insecticidal 5-substituted-2,4-diaminopyrimidine derivatives

An insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a compound of the formula: STR1 wherein R, R1, R2, R3, R7, R8, m, n, and p are as defined herein, and agriculturally acceptable salts thereof, and methods of using the same.

Pyrimidine N-Oxides. VI. The Ionization Constants of Pyrimidine-2,4-diamine N-Oxides

The ionization constants of some pyrimidine-2,4-diamines and their N-oxides, including the drugs 'trimethoprim' and 'minoxidil', are reported.The syntheses of several pyrimidine-2,4-diamine N-oxides are described.

2,4-Diamino-6-methyl-5-(halophenylazo) pyrimidines

Compounds comprising selected 2,4-diamino-6-methyl-5-(halophenylazo) pyrimidines which are highly active as folic acid antagonists. The compounds include 2,4-diamino-6-methyl-5-(m-chlorophenylazo) pyrimidine; 2,4-diamino-6-methyl-5-(p-bromophenylazo) pyri