- Synthesis and characterization of new highly fluorinated phosphoramidates
-
A one-pot synthesis of new bis(polyfluoroalkyl)dialkylaminophosphoramidates (RF(CH2)2O)2P(O)NR2 (1–6) (RF = C6F13, NR2 = NC5H10 (1), N
- Laribi,Sanhoury,Mechi,Merlet,Chehidi
-
-
Read Online
- A new mechanism for nucleophilic substitution at a thiophosphoryl centre revealed by the reaction of diisopropylamine with PSCl3
-
The reaction of PSCl3 with Pri2NH at 60 °C affords the disubstitution product (Pri2N) 2P(S)Cl without first forming the monosubstitution product Pr i2NP(S)Cl2/su
- Harger, Martin J. P.
-
p. 2863 - 2865
(2007/10/03)
-
- Reactions of phosphorodiamidous acid esters with α-halocarbonyl compounds
-
Reactions of ethyl and tert-butyl phosphorodiamidites with chloroacetone, bromoacetone, and α-chloroethyl acetate were studied. The reaction pathway is determined by the structure of the intermediate quasiphosphonium compound responsible for the formation
- Sal'keeva,Nurmaganbetova,Kurmanaliev,Gazizov
-
p. 1760 - 1763
(2007/10/03)
-
- Advances in trifluoromethylating phosphorus compounds
-
The System CF3IMe3P is re-investigated and Me2PCF3, Me4P+I-, (CF3)2PMe3, Me3PI2, [Me3(CF3)P]+I- are found as products. Using CF3Br/P(NEt2)3 the phosphines R12PCF3 and R1P(CF3)2 (e.g. R1 = Me, iPr, NEt2) can be obtained which are precursors either for phosphoranes (e.g. 1,2λ5σ5-oxaphosphetanes) or phosphonium salts (e.g. [R12(Me)PCF3]+X- or [R1(Me)P(CF3)2X-]. The latter are deprotonated to furnish methylene phosphoranes R12(CH2=)PCF3 or R1(CH2=)P(CF3)2, reactive synthons. From CF3Br/ P(NEt2)3/P(OPh)3 the phosphine P(CF3)3 is available, which turned out to be a potent electrophile. Amido phospites ROP(NEt2)2 and halides R2X (R2= CCl2CF3, X= Cl; R2= CF=CFCF3, X= F; R2= C6F5, X= Br, I; R2= C(CF3)3, X= Br; R2= SCF3, X= CF3) undergo an ARBUZOV reaction.
- Kolomeitsev, Alexander,Goerg, Michaela,Dieckbreder, Uwe,Lork, Enno,Roeschenthaler, Gerd-Volker
-
p. 597 - 600
(2007/10/03)
-
- Glutathione-S-transferase activates novel alkylating agents
-
Alkylating agents which are activated by glutathione-S-transferases (GSTs) have been designed and synthesized. The model compound γ-glutamyl-α-amino- β-[(2-ethyl N,N,N',N'-tetraethyl- phosphorodiamidate)sulfonyl]propionylglycine (1) and the nitrogen musta
- Lyttle,Satyam,Hocker,Bauer,Caldwell,Hui,Morgan,Mergia,Kauvar
-
p. 1501 - 1507
(2007/10/02)
-
- REACTIONS OF ESTER AND ACID AMIDES OF TRIVALENT PHOSPHORUS WITH α-HALOALDEHYDES
-
tert-Butyltetraethyldiamido phosphite reacted with chloral and mono- and dichloroacetaldehyde via two pathways: to form tetraethyldiamido chlorophosphate and the corresponding tetraethyldiamidophosphoric acid vinyl ester.When the reaction was carried out
- Aleksandrova, I. A.,Sal'keeva, L. K.,Chugunov, Yu. V.,Gazizov, T. Kh.
-
p. 501 - 505
(2007/10/02)
-
- PHOSPHORYLATION COMPETITIVE DE DERIVES D'UREES/THIOUREES ET DE CARBAMATES/THIOCARBAMATES EN RELATION AVEC LE MODELE O-PHOSPHOBIOTINE.
-
The phosphorylation of a number of heterocyclic substrates, such as ureas and carbamates, and their sulfur analogues, has been investigated with the object of clarifying previous results concerning the site of phosphorylation of this type of substrate, wh
- Etemad-Moghadam, G.,Klaebe, A.,Perie, J. J.
-
-