1794-24-7

Usage

Chemical Properties

clear colorless to light yellow liquid

Uses

suzuki reaction

InChI:InChI=1/C8H20ClN2OP/c1-5-10(6-2)13(12-9)11(7-3)8-4/h5-8H2,1-4H3

Upstream product

• 1498-54-0 N,N-diethylphosphoramidous dichloride 
• 109-89-7 diethylamine 
• 3560-15-4 tetraethyldiamidophosphite 
• 2632-88-4 ethyl N,N'-tetraethyldiamidophosphite 
• 79-02-7 2,2-dichloroacetaldehyde 
• 118818-64-7 tetraethyldiamidophosphorous acid tert-butyl ester 
• 5775-33-7 N-chlorodiethylamine 
• 354-58-5 1,1,1-Trichloro-2,2,2-trifluoroethane 
• 66954-57-2 benzyl tetraethylphosphorodiamidite 
• 205444-26-4 2,2,2-trifluoroethyl bis(diethylamido)phosphite 
• 2283-11-6 hexaethylphosphoric triamide 
• 78-95-5 chloroacetone 
• 75-87-6 chloral 
• 107-20-0 2-chloroethanal 

Downstream Products

• 562-17-4 tetraethylphosphorodiamidic fluoride 
• 18551-98-9 Thiophosphorsaeure-S-phenylester-bis-diaethylamid 
• 67154-33-0 (2-thioxo-benzothiazol-3-yl)-phosphonic acid bis-diethylamide 
• 4519-33-9 phenyl N,N,N',N'‐tetraethylphosphorodiamidate 
• 3185-66-8 N,N,N',N'-tetraethyl-N''-phenylphosphoric triamide 

Relevant academic research and scientific papers

Synthesis and characterization of new highly fluorinated phosphoramidates

A one-pot synthesis of new bis(polyfluoroalkyl)dialkylaminophosphoramidates (RF(CH2)2O)2P(O)NR2 (1–6) (RF = C6F13, NR2 = NC5H10 (1), N

A new mechanism for nucleophilic substitution at a thiophosphoryl centre revealed by the reaction of diisopropylamine with PSCl3

The reaction of PSCl3 with Pri2NH at 60 °C affords the disubstitution product (Pri2N) 2P(S)Cl without first forming the monosubstitution product Pr i2NP(S)Cl2/su

Reactions of phosphorodiamidous acid esters with α-halocarbonyl compounds

Reactions of ethyl and tert-butyl phosphorodiamidites with chloroacetone, bromoacetone, and α-chloroethyl acetate were studied. The reaction pathway is determined by the structure of the intermediate quasiphosphonium compound responsible for the formation

Advances in trifluoromethylating phosphorus compounds

The System CF3IMe3P is re-investigated and Me2PCF3, Me4P+I-, (CF3)2PMe3, Me3PI2, [Me3(CF3)P]+I- are found as products. Using CF3Br/P(NEt2)3 the phosphines R12PCF3 and R1P(CF3)2 (e.g. R1 = Me, iPr, NEt2) can be obtained which are precursors either for phosphoranes (e.g. 1,2λ5σ5-oxaphosphetanes) or phosphonium salts (e.g. [R12(Me)PCF3]+X- or [R1(Me)P(CF3)2X-]. The latter are deprotonated to furnish methylene phosphoranes R12(CH2=)PCF3 or R1(CH2=)P(CF3)2, reactive synthons. From CF3Br/ P(NEt2)3/P(OPh)3 the phosphine P(CF3)3 is available, which turned out to be a potent electrophile. Amido phospites ROP(NEt2)2 and halides R2X (R2= CCl2CF3, X= Cl; R2= CF=CFCF3, X= F; R2= C6F5, X= Br, I; R2= C(CF3)3, X= Br; R2= SCF3, X= CF3) undergo an ARBUZOV reaction.

Glutathione-S-transferase activates novel alkylating agents

Alkylating agents which are activated by glutathione-S-transferases (GSTs) have been designed and synthesized. The model compound γ-glutamyl-α-amino- β-[(2-ethyl N,N,N',N'-tetraethyl- phosphorodiamidate)sulfonyl]propionylglycine (1) and the nitrogen musta

REACTIONS OF ESTER AND ACID AMIDES OF TRIVALENT PHOSPHORUS WITH α-HALOALDEHYDES

tert-Butyltetraethyldiamido phosphite reacted with chloral and mono- and dichloroacetaldehyde via two pathways: to form tetraethyldiamido chlorophosphate and the corresponding tetraethyldiamidophosphoric acid vinyl ester.When the reaction was carried out