1794-24-7Relevant articles and documents
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Ko,E.C.F.,Robertson,R.E.
, p. 597 - 603 (1973)
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Crunden,E.W.,Hudson,R.F.
, p. 3591 - 3599 (1962)
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Reactions of phosphorodiamidous acid esters with α-halocarbonyl compounds
Sal'keeva,Nurmaganbetova,Kurmanaliev,Gazizov
, p. 1760 - 1763 (2007/10/03)
Reactions of ethyl and tert-butyl phosphorodiamidites with chloroacetone, bromoacetone, and α-chloroethyl acetate were studied. The reaction pathway is determined by the structure of the intermediate quasiphosphonium compound responsible for the formation
Glutathione-S-transferase activates novel alkylating agents
Lyttle,Satyam,Hocker,Bauer,Caldwell,Hui,Morgan,Mergia,Kauvar
, p. 1501 - 1507 (2007/10/02)
Alkylating agents which are activated by glutathione-S-transferases (GSTs) have been designed and synthesized. The model compound γ-glutamyl-α-amino- β-[(2-ethyl N,N,N',N'-tetraethyl- phosphorodiamidate)sulfonyl]propionylglycine (1) and the nitrogen musta