180403-11-6

Basic information

• Product Name: 4,5-diphenyl-N-(2-phenylethyl)-1,3-thiazol-2-amine
• Synonyms: 4,5-diphenyl-N-(2-phenylethyl)-1,3-thiazol-2-amine
• CAS NO: 180403-11-6
• Molecular Formula: C23H20N2S
• Molecular Weight: 356.4833
• Mol File: 180403-11-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,5-diphenyl-N-(2-phenylethyl)-1,3-thiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-diphenyl-N-(2-phenylethyl)-1,3-thiazol-2-amine(180403-11-6)
• EPA Substance Registry System: 4,5-diphenyl-N-(2-phenylethyl)-1,3-thiazol-2-amine(180403-11-6)

Safety Data

• Hazardous Substances Data: 180403-11-6(Hazardous Substances Data)

Upstream product

• 6815-00-5 N-(2-phenylethyl)thiourea 
• 1484-50-0 desyl bromide 
• 333-20-0 potassium thioacyanate 
• 24722-38-1 β-phenethylammonium acetate 

Relevant articles and documents

A convenient procedure for the solution phase preparation of 2-aminothiazole combinatorial libraries

A convenient procedure for the solution phase preparation of 2-aminothiazole combinatorial libraries is described. The library preparation is simple, practical, and effective, generating compounds based around a known pharmacophore in high yield and purit

One pot synthesis using supported reagents system KSCN/SiO 2-RNH3OAc/Al2O3: Synthesis of 2-aminothiazoles and N-allylthioureas

A simple and efficient method has been developed for the synthesis of 2-aminothiazoles and N-allylthioureas from commercially available materials in one pot by using a supported reagents system, KSCN/SiO2-RNH 3OAc/Al2O3, in which α-halo ketone reacts first KSCN/SiO2 and the product, α-thiocyanatoketone, reacts with RNH3OAc/Al2O3 to give the final product, 2-aminothiazoles, in good yield and allyl bromide reacts with KSCN/SiO 2 and the product, allyl isothiocyanate, reacts with RNH 3OAc/Al2O3 to give N-allylthiourea.