Synthesis of β-aminosulfonopeptides activated through selective N-nitration of a taurine amide unit
β-Sulfonopeptides bearing a taurine in place of a penultimate amino acid unit were designed and synthesized as inhibitors of D-alanyl-D-alanine transpeptidase; N-nitration of the sulfonamide bond in the presence of multiple carboxamide groups was selectively accomplished through use of NO2BF4.
Paik, Seunguk,White, Emil H.
p. 4663 - 4666
(2007/10/03)
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