181283-83-0

Basic information

• Product Name: 6-Quinolinecarboxylicacid,5-amino-(9CI)
• Synonyms: 6-Quinolinecarboxylicacid,5-amino-(9CI)
• CAS NO: 181283-83-0
• Molecular Formula: C₁₀H₈N₂O₂
• Molecular Weight: 188.18272
• Product Categories: AMINOACID
• Mol File: 181283-83-0.mol

Chemical Properties

• Melting Point: 218.5 °C (decomp)
• Boiling Point: 395.2±37.0 °C(Predicted)
• Appearance: /
• Density: 1.430±0.06 g/cm3(Predicted)
• PKA: 3.79±0.30(Predicted)
• CAS DataBase Reference: 6-Quinolinecarboxylicacid,5-amino-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Quinolinecarboxylicacid,5-amino-(9CI)(181283-83-0)
• EPA Substance Registry System: 6-Quinolinecarboxylicacid,5-amino-(9CI)(181283-83-0)

Safety Data

• Hazardous Substances Data: 181283-83-0(Hazardous Substances Data)

Upstream product

• 23141-61-9 6-methyl-5-nitroquinoline 
• 91-62-3 6-methylquinoline 

Downstream Products

• 873970-05-9 5-mercapto-quinoline-6-carboxylic acid 
• 91118-90-0 3-(4-Methoxy-phenyl)-2-[(E)-2-(4-methoxy-phenyl)-vinyl]-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-89-7 3-(3-Nitro-phenyl)-2-((E)-styryl)-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-91-1 3-(4-Methoxy-phenyl)-2-((E)-2-p-tolyl-vinyl)-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-92-2 3-(4-Chloro-phenyl)-2-[(E)-2-(4-chloro-phenyl)-vinyl]-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-87-5 3-(4-Methoxy-phenyl)-2-((E)-styryl)-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-85-3 2-[(E)-2-(4-Chloro-phenyl)-vinyl]-3-phenyl-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-88-6 2-((E)-Styryl)-3-p-tolyl-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-84-2 3-Phenyl-2-((E)-2-p-tolyl-vinyl)-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-82-0 3-Phenyl-2-((E)-styryl)-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-97-7 3-(2-Chloro-phenyl)-2-methyl-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-98-8 3-(4-Chloro-phenyl)-2-methyl-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-99-9 3-Benzyl-2-methyl-3H-pyrido[2,3-h]quinazolin-4-one 
• 91118-95-5 2-Methyl-3-o-tolyl-3H-pyrido[2,3-h]quinazolin-4-one 

Relevant articles and documents

Selenium-catalyzed intramolecular atom- And redox-economical transformation ofo-nitrotoluenes into anthranilic acids

Anthranilic acids (AAs) are significant basic chemicals used in pharmaceuticals, agrochemicals, dyes, fragrances,etc. Superfluous steps are always involved in obtaining AAs. Herein, we demonstrate a straightforward strategy to transform abundanto-nitrotoluenes into biologically and pharmaceutically significant AAs without any extra reductants, oxidants and protecting groups. Various sensitive groups, such as halogens, sulfide, aldehyde, pyridines, quinolines,etc., can be tolerated in this transformation. A hundred-gram-scale operation is realized efficiently with almost quantitative selenium recycling. Further mechanistic studies and DFT calculations disclosed the proposed atom-exchange processes and the key roles of the selenium species.

Anthranilic acid and derivatives thereof as well as synthesis method and application thereof

In the reaction solvent, o-methyl (hetero) aryl nitro compound is taken as a reaction raw material and is used for water. The anthranilic acid and its derivatives are synthesized by the action of a catalyst, a base and an additive. The synthetic method has the advantages of cheap and easily available raw materials, simple reaction operation, high yield and excellent functional group tolerance, and provides a simple and efficient method for synthesizing o-aminobenzoic acid which is widely used in the aspects of dyes, medicines, pesticides, spices and the like. The invention further discloses the anthranilic acid and derivatives and application thereof, and has a wide application prospect.