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181951-92-8

FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE is a specialized chemical compound utilized as a building block in the synthesis of peptides. It features a fluorenylmethyloxycarbonyl (FMOC) protecting group that shields against undesired reactions during peptide synthesis. FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE also includes a tert-butoxycarbonyl (Boc) group that serves as a protective agent for the amine, with a methoxy group acting as a connector between the Boc group and the phenylalanine amino acid. Known for its stability and compatibility with solid-phase peptide synthesis methods, it is widely employed in the creation of peptides for research and pharmaceutical applications.

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  • 181951-92-8 Structure

  • Basic information

    1. Product Name: FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE
    2. Synonyms: Fmoc-4-(tert-butoxycarbonylmethoxy)-L-Phe-OH;FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE;Fmoc-4-(tert-butoxycarbonylmethoxy)-Phe-OH;Fmoc-4-(Boc-methoxy)-L-phenylalanine;N-Fmoc-4-(tert-butoxycarbonylmethoxy)-L-phenylalanine
    3. CAS NO:181951-92-8
    4. Molecular Formula: C30H31NO7
    5. Molecular Weight: 517.57
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 181951-92-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 699.6 °C at 760 mmHg
    3. Flash Point: 376.9 °C
    4. Appearance: /
    5. Density: 1.251 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE(181951-92-8)
    11. EPA Substance Registry System: FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE(181951-92-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 181951-92-8(Hazardous Substances Data)

181951-92-8 Usage

Uses

Used in Pharmaceutical Industry:
FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE is used as a key component in the synthesis of peptides for various pharmaceutical applications. Its role is crucial for the development of new drugs and therapeutic agents, given its ability to facilitate the creation of stable and effective peptide-based compounds.
Used in Research Applications:
In the research field, FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE is used as a fundamental building block for the synthesis of peptides that are essential for scientific studies. It aids researchers in exploring the properties and potential applications of peptides, contributing to advancements in biotechnology and medicine.
Used in Peptide Synthesis:
FMOC-4-(TERT-BUTOXYCARBONYLMETHOXY)-L-PHENYLALANINE is used as a protected amino acid in peptide synthesis. The presence of the FMOC and Boc protecting groups allows for the controlled addition of phenylalanine to growing peptide chains, ensuring the desired peptide sequence is achieved without premature termination or side reactions. This makes it an indispensable tool in the solid-phase peptide synthesis process.

Check Digit Verification of cas no

The CAS Registry Mumber 181951-92-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,9,5 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 181951-92:
(8*1)+(7*8)+(6*1)+(5*9)+(4*5)+(3*1)+(2*9)+(1*2)=158
158 % 10 = 8
So 181951-92-8 is a valid CAS Registry Number.

181951-92-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Fmoc-4-(Boc-methoxy)-L-phenylalanine

1.2 Other means of identification

Product number -
Other names (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[4-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]phenyl]propanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:181951-92-8 SDS

181951-92-8Downstream Products

181951-92-8Relevant articles and documents

Enantioselective synthesis of nonphosphorus-containing phosphotyrosyl mimetics and their use in the preparation of tyrosine phosphatase inhibitory peptides

Burke Jr., Terrence R.,Yao, Zhu-Jun,Zhao, He,Milne, George W. A.,Wu, Li,Zhang, Zhong-Yin,Voigt, Johannes H.

, p. 9981 - 9994 (2007/10/03)

Three new L-amino acid analogues 12, 18 and 25 have been prepared in protected form suitable for incorporation into peptides by solid-phase synthesis using Fmoc protocols. These agents represent nonphosphorus- containing phosphotyrosyl (pTyr) mimetics, wh

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