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183500-70-1

1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE is a chemical compound that belongs to the class of piperazin-2-one derivatives. It is characterized by a molecular formula of C10H12ClN2O and a molecular weight of 214.67 g/mol. 1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE features a piperazine ring with a chlorine-substituted phenyl group and a keto group. Its unique structure and properties make it a promising candidate for various applications in the pharmaceutical and chemical industries.

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  • 183500-70-1 Structure

  • Basic information

    1. Product Name: 1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE
    2. Synonyms: 1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE;1-(3-chlorophenyl)-2-piperazinone;1-(3-Chlorophenyl)Piperazin-2-one(HCl);1-(3-Chlorophenyl)-2-piperazinone HCl
    3. CAS NO:183500-70-1
    4. Molecular Formula: C10H11ClN2O
    5. Molecular Weight: 210.66
    6. EINECS: N/A
    7. Product Categories: pharmacetical
    8. Mol File: 183500-70-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 443.887 °C at 760 mmHg
    3. Flash Point: 222.255 °C
    4. Appearance: /
    5. Density: 1.268 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.574
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE(183500-70-1)
    12. EPA Substance Registry System: 1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE(183500-70-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 183500-70-1(Hazardous Substances Data)

183500-70-1 Usage

Uses

Used in Pharmaceutical Industry:
1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE is used as a building block for the synthesis of diverse organic compounds, including potential drug candidates. Its unique structure and properties make it an interesting target for further research and development in the pharmaceutical field.
Used in Chemical Industry:
1-(3-CHLORO-PHENYL)-PIPERAZIN-2-ONE is used as a potential drug candidate due to its unique structure and properties. Its physical and chemical properties, as well as its potential biological activities, make it a valuable compound for exploration in the chemical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 183500-70-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,3,5,0 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 183500-70:
(8*1)+(7*8)+(6*3)+(5*5)+(4*0)+(3*0)+(2*7)+(1*0)=121
121 % 10 = 1
So 183500-70-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H11ClN2O/c11-8-2-1-3-9(6-8)13-5-4-12-7-10(13)14/h1-3,6,12H,4-5,7H2

183500-70-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(3-chlorophenyl)piperazin-2-one

1.2 Other means of identification

Product number -
Other names 2-Piperazinone,1-(3-chlorophenyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:183500-70-1 SDS

183500-70-1Relevant articles and documents

QUATERNARY LACTAM COMPOUND AND PHARMACEUTICAL USE THEREOF

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Paragraph 0514-0515; 0517, (2021/02/05)

A quaternary lactam compound of formula (I). The compound is used in the manufacture of a medicament for the treatment and/or prevention of thrombotic or thromboembolic disorders.

Method of treating cancer

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Page/Page column 95, (2010/02/12)

The present invention relates to methods of treating cancer using a combination of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either s

Method of treating cancer

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, (2008/06/13)

The present invention relates to methods of treating cancer using a combination of a compound which is a PSA conjugate and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at least two therapeutic agents selected from a group consisting of a compound which is a PSA conjugate and a compound which is a inhibitor of prenyl-protein transferase. The invention also relates to methods of preparing such compositions.

INHIBITORS OF PRENYL-PROTEIN TRANSFERASE

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, (2008/06/13)

The present invention is directed to compounds which inhibit prenyl-protein transferases, farnesyl-protein transferase and geranylgeranyl-protein transferase type I, and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and geranylgeranyl-protein transferase type I and the prenylation of the oncogene protein RAS.

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

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, (2008/06/13)

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras

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