185339-08-6Relevant articles and documents
Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine
Inada, Haruki,Shibuya, Masatoshi,Yamamoto, Yoshihiko
, p. 11047 - 11059 (2020/10/12)
The transamination of α-keto acids with 2-phenylglycine is an effective methodology for directly synthesizing unprotected α-amino acids. However, the synthesis of 2-arylglycines by transamination is problematic because the corresponding products, 2-arylglycines, transaminate the starting arylglyoxylic acids. Herein, we demonstrate the use of commercially available l-2-(2-chlorophenyl)glycine as the nitrogen source in the transamination of arylglyoxylic acids, producing the corresponding 2-arylglycines without interference from the undesired self-transamination process.
Understanding of the mode of action of FeIII-EDDHA as iron chlorosis corrector based on its photochemical and redox behavior
Gomez-Galleso, Mar,Pellico, Daniel,Ramirez-Lopez, Pedro,Mancheno, J. Maria,Romano, Santiago,De La Torre, Maria C.,Sierra, Miguel A.
, p. 5997 - 6005 (2007/10/03)
The very low reduction potential of the chelate FeIII-EDDHA (EDDHA= ethylenediamine N,N'-bis(2-hydroxy)phenylacetic acid) makes it unreactive in photochemically or chemically induced electron transfer processes. The lack of reactivity of this c
Highly diastereoselective synthesis of arylglycine derivatives via TFA-promoted Friedel-Crafts reactions of phenols with cyclic glyoxylate imines
Chen, Yong-Jun,Lei, Fei,Liu, Li,Wang, Dong
, p. 7609 - 7614 (2007/10/03)
Optically active α-arylglycine derivatives were synthesized by Br?nsted acid (TFA)-promoted Friedel-Crafts reaction of various phenols with chiral cyclic glyoxylate imines (2a-c), followed by deprotection with Pd(OH)2/C under H2. The diastereoselectivities of the initially formed F-C reaction products are up to 99%.
2-HYDROXYPHENYLALKYLAMINE DERIVATIVES AND MAILLARD REACTION INHIBITORS
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, (2008/06/13)
The present invention relates to a 2-hydroxyphenyl alkylamine derivative represented by the general formula: wherein R1, R2, R3and R4are the same or different: and each represents a hydrogen atom, a lower alkyl
HYDROXYLATION OF AROMATIC RINGS IN AN AQUEOUS SOLUTION INDUCED BY ARGON ARC PLASMA
Takasaki, Michiaki,Harada, Kaoru
, p. 885 - 888 (2007/10/02)
Plasma-induced reaction in an aqueous solution of phenyl-containing amino acids resulted in the formation of several hydroxyphenyl amino acids, which was explained by the action of hydroxyl radicals generated by decomposition of water molecules by the high energy plasma.
HYDROXYLATION REACTION OF AROMATIC RINGS IN AQUEOUS SOLUTION INDUCED BY HYDROGEN-OXYGEN FLAME
Takasaki, Michiaki,Nomoto, Shinya,Harada, Kaoru
, p. 1629 - 1632 (2007/10/02)
It was found that direct hydroxylation of aromatic rings proceeded in aqueous solution of phenyl-containing amino acids by using hydrogen-oxygen flame and that the active species of the reaction could be considered as hydroxyl radicals generated in the burning flame.
3-Amidocoumaranones
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, (2008/06/13)
3-Amidocoumaranones which may be substituted in the benzene ring by halo or alkyl; the compounds are obtained by treating an appropriate 2-hydroxyphenylacetic acid lactone with nitrous acid or with an ester, salt or chloride of nitrous acid in an acid med
