1857-19-8

Basic information

• Product Name: 2-amino-N,N-dimethylacetamide
• Synonyms: N,N-Dimethyl-2-aminoacetamide;2-diazenyl-N,N-dimethylacetamide;2-Amino-N,N-dimethylacetamide;Glycine dimethylamide, 97%;A80236;N~1~,N~1~-dimethylglycinamide(SALTDATA: HCl);N~1~,N~1~-dimethylglycinamide 1HCl;2-aMino-N,N-diMethylacetaMide hcl
• CAS NO: 1857-19-8
• Molecular Formula: C₄H₁₀N₂O
• Molecular Weight: 102.13
• Mol File: 1857-19-8.mol

Chemical Properties

• Boiling Point: 181.3oC at 760 mmHg
• Flash Point: 63.5oC
• Appearance: /
• Density: 0.995±0.06 g/cm3(Predicted)
• Vapor Pressure: 0.856mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.46±0.10(Predicted)
• Sensitive: Air Sensitive
• CAS DataBase Reference: 2-amino-N,N-dimethylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-N,N-dimethylacetamide(1857-19-8)
• EPA Substance Registry System: 2-amino-N,N-dimethylacetamide(1857-19-8)

Safety Data

• HazardClass: 8
• Hazardous Substances Data: 1857-19-8(Hazardous Substances Data)

Usage

Uses

Glycine dimethylamide is used as pharmaceutical intermediate.

InChI:InChI=1/C4H10N2O/c1-6(2)4(7)3-5/h3,5H2,1-2H3/p+1

Upstream product

• 2185-00-4 1,3-oxazolidine-2,5-dione 
• 124-40-3 dimethyl amine 
• 72287-76-4 N-[2-(dimethylamino)-2-oxoethyl]carbamic acid 1,1-dimethylethyl ester 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 68-12-2 N,N-dimethyl-formamide 
• 167303-60-8 N-Benzyloxycarbonylglycine dimethylamide 

Downstream Products

• 340011-61-2 N,N-dimethyl-2-[6-phenyl-2-(4-trifluoromethylphenyl)-4-pyrimidinylamino]acetamide 
• 1034257-52-7 2-{3-[4-bromo-2-((3R,5S)-3,5-dimethyl-piperidine-1-carbonyl)-phenyl]-ureido}-N,N-dimethyl-acetamide 
• 335154-66-0 1-(4-[N-(2-Dimethylamino-2-oxoethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine 
• 1357917-82-8 2-[(3-methylbenzylidene)amino]-N,N-dimethylacetamide 
• 1357917-83-9 2-[(2-methylbenzylidene)amino]-N,N-dimethylacetamide 
• 1357917-78-2 2-[(4-bromobenzylidene)amino]-N,N-dimethylacetamide 
• 1357917-80-6 2-[(4-methoxybenzylidene)amino]-N,N-dimethylacetamide 
• 1357917-76-0 2-benzylideneamino-N,N-dimethylacetamide 

Relevant articles and documents

Highly Selective and Sensitive Detection of Biogenic Defense Phytohormone Salicylic Acid in Living Cells and Plants Using a Novel and Viable Rhodamine-Functionalized Fluorescent Probe

Detecting plant-derived signal molecules using fluorescent probes is a key topic and a huge challenge for scientists. Salicylic acid (SA), a vital plant-derived defense hormone, can activate global transcriptional reprogramming to systemically express a network of prominent pathogenesis-related proteins against invasive microorganisms. This strategy is called systemic acquired resistance (SAR). Therefore, monitoring the dynamic fluctuations of SA in subcellular microenvironments can advance our understanding of different physiological and pathological functions during the SA-induced SAR mechanism, thus benefiting the discovery and development of novel immune activators that contribute to crop protection. Here, detection of signaling molecule SA in plant callus tissues was first reported and conducted by a simple non-fluorescent rhodamine-tagged architecture bearing a flexible 2-amino-N,N-dimethylacetamide pattern. This study can markedly advance and promote the usage of fluorescent SA probes for distinguishing SA in the plant kingdom.

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Structure-activity relationships of the peptide deformylase inhibitor BB-3497: Modification of the P2′ and P3′ side chains

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