185913-98-8

Basic information

• Product Name: (R)-(+)-5,5'-DICHLORO-6,6'-DIMETHOXY-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BIPHENYL
• Synonyms: (-)-5,5'-DICHLORO-2,2'-BIS(DIPHENYLPHOSPHINO)-6,6'-DIMETHOXY-1,1'-BIPHENYL;(+)-5,5'-DICHLORO-2,2'-BIS(DIPHENYLPHOSPHINO)-6,6'-DIMETHOXY-1,1'-BIPHENYL;(-)-(5,5'-DICHLORO-6,6'-DIMETHOXY-1,1'-BIPHENYL)-2,2'-DIYL-BIS(DIPHENYLPHOSPHINE);(+)-(5,5'-DICHLORO-6,6'-DIMETHOXY-1,1'-BIPHENYL)-2,2'-DIYL-BIS(DIPHENYLPHOSPHINE);(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-5,5'-DICHLORO-6,6'-DIMETHOXY-1,1'-BIPHENYL;(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-5,5'-DICHLORO-6,6'-DIMETHOXY-1,1'-BIPHENYL;(R)-CL-MEO-BIPHEP;(R)-(+)-5,5'-DICHLORO-6,6'-DIMETHOXY-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BIPHENYL
• CAS NO: 185913-98-8
• Molecular Formula: C₃₈H₃₀Cl₂O₂P₂
• Molecular Weight: 651.5
• Product Categories: Chiral Phosphine;MeOBIPHEP Series
• Mol File: 185913-98-8.mol

Chemical Properties

• Melting Point: 176-180 °C
• Boiling Point: 678.2±55.0 °C(Predicted)
• Appearance: yellow-white/Powder
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (R)-(+)-5,5'-DICHLORO-6,6'-DIMETHOXY-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-5,5'-DICHLORO-6,6'-DIMETHOXY-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BIPHENYL(185913-98-8)
• EPA Substance Registry System: (R)-(+)-5,5'-DICHLORO-6,6'-DIMETHOXY-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BIPHENYL(185913-98-8)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10-23
• Hazardous Substances Data: 185913-98-8(Hazardous Substances Data)

Usage

Reactions

Ligand used in the ruthenium catalyzed, enantioselective hydrogenation of alkenes, carbonyls,and imines. Ligand used in the rhodium-catalyzed cyclization of acetylenic aldehydes. Ligand used in the iridium-catalyzed hydrogenative coupling of alkynes to aromatic and aliphatic N-arylsulfonyl aldimines. Asymmetric Cu-catalyzed propargylic substitution with amines,4a and enamines.4b Catalytic desymmetrizing intramolecular Heck reaction. Assembly of 1,3-polyols. Pd-catalyzed diastereo/enantioselective allylic alkylations of ketone enolates.

Upstream product

• 185836-54-8 (+)-(5,5'-dichloro-6,6'-dimethoxybiphenyl-2,2'-diyl)-bis(diphenylphosphine oxide) 

Downstream Products

• 1415934-50-7 C₄₈H₃₇Cl₂IrN₂O₈P₂ 

Relevant articles and documents

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