[4-Chloro-2-(3-chloro-6-diphenylphosphanyl-2-methoxyphenyl)-3-methoxyphenyl]-diphenylphosphane

Base Information

• Chemical Name: [4-Chloro-2-(3-chloro-6-diphenylphosphanyl-2-methoxyphenyl)-3-methoxyphenyl]-diphenylphosphane
• CAS No.: 185913-98-8
• Molecular Formula: C38H30 Cl2 O2 P2
• Molecular Weight: 651.509
• European Community (EC) Number: 811-310-8,811-677-4
• Nikkaji Number: J2.471.660K,J2.182.860B
• Mol file: 185913-98-8.mol

Synonyms:185913-98-8;185913-97-7;(S)-(-)-5,5'-Dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl;[4-chloro-2-(3-chloro-6-diphenylphosphanyl-2-methoxyphenyl)-3-methoxyphenyl]-diphenylphosphane;(R)-MeO-Cl-BIPHEP;(r)-(+)-5,5'-dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl;MFCD03426987;(R)-(+)-5,5/'-DICHLORO-6,6/'-DIMETHOXY-2,2/'-BIS(DIPHENYLPHOSPHINO)-1,1/'-BIPHENYL;(R)-(-)-Cl-MeO-BIPHEP;(R)-(5,5'-Dichloro-6,6'-dimethoxy-[1,1'-biphenyl]-2,2'-diyl)bis(diphenylphosphine);(S)-(-)-Cl-MeO-BIPHEP;GCBRCSSVOVNEIX-UHFFFAOYSA-N;SCHEMBL1414671;SY068468;SY073807;CS-0086659;CS-0087063;E76943;J-011923;J-011924;5,5'-Dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl;(-)-(5,5'-Dichloro-6,6'-dimethoxy-1,1'-biphenyl)-2,2'-diyl-bis(diphenylphosphine);(-)-2,2'-Bis(diphenylphosphino)-5,5'-dichloro-6,6'-dimethoxy-1,1'-biphenyl;(R)-(+)-5,5'-Dichloro-2,2'-bis(diphenylphosphino)- 6,6'-dimethoxy-1,1'-biphenyl;(R)-(+)-5,5'-Dichloro-2,2'-bis(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl;(S)-(+)-5,5'-Dichloro-2,2'-bis(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl;(R)-(+)-5,5'-Dichloro-2,2'-bis(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl, >=95.0% (H-NMR);(R)-(5,5 inverted exclamation mark -Dichloro-6,6 inverted exclamation mark -dimethoxy-[1,1 inverted exclamation mark -biphenyl]-2,2 inverted exclamation mark -diyl)bis(diphenylphosphine);(S )-(5,5 inverted exclamation mark -Dichloro-6,6 inverted exclamation mark -dimethoxy-[1,1 inverted exclamation mark -biphenyl]-2,2 inverted exclamation mark -diyl)bis(diphenylphosphine);(S)-(-)-5,5'-Dichloro-2,2'-bis(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl, >=97.0% (H-NMR);[3',5-DICHLORO-6'-(DIPHENYLPHOSPHANYL)-2',6-DIMETHOXY-[1,1'-BIPHENYL]-2-YL]DIPHENYLPHOSPHANE

Chemical Property of [4-Chloro-2-(3-chloro-6-diphenylphosphanyl-2-methoxyphenyl)-3-methoxyphenyl]-diphenylphosphane

Chemical Property:

• Melting Point: 176-180 °C
• Boiling Point: 678.2±55.0 °C(Predicted)
• Flash Point: 364oC
• PSA: 45.64000
• LogP: 8.19400
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 10.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 9
• Exact Mass: 650.1098096
• Heavy Atom Count: 44
• Complexity: 735

Purity/Quality:

97%,99%ee ^*data from raw suppliers

(S)-(-)-5,5'-Dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl, min. 95% (S)-Cl-MeO-BIPHEP ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=C(C=CC(=C1C2=C(C=CC(=C2OC)Cl)P(C3=CC=CC=C3)C4=CC=CC=C4)P(C5=CC=CC=C5)C6=CC=CC=C6)Cl

Technology Process of [4-Chloro-2-(3-chloro-6-diphenylphosphanyl-2-methoxyphenyl)-3-methoxyphenyl]-diphenylphosphane

There total 2 articles about [4-Chloro-2-(3-chloro-6-diphenylphosphanyl-2-methoxyphenyl)-3-methoxyphenyl]-diphenylphosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(+)-(5,5'-dichloro-6,6'-dimethoxybiphenyl-2,2'-diyl)-bis(diphenylphosphine oxide) (185836-54-8,185913-95-5,185913-96-6) → (R)-Cl-MeO-BiPhep (185913-97-7,185913-98-8,377773-83-6)

Guidance literature:

With sodium hydroxide; tributyl-amine; trichlorosilane; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; water;

Reference yield:

→ (R)-Cl-MeO-BiPhep (185913-97-7,185913-98-8,377773-83-6)

Guidance literature:

Reference yield: 91.0%

dichloro(benzene)ruthenium(II) dimer (37366-09-9) + (S)-(-)-5,5'-dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl (185913-98-8) + (S)-α-methyl-1H-benzimidazole-2-methanamine (135875-04-6,163959-79-3) → trans-RuCl2[(S)-Cl-MeO-BIPHEP][(S)-Me-bimaH]

Guidance literature:

dichloro(benzene)ruthenium(II) dimer; (S)-(-)-5,5'-dichloro-6,6'-dimethoxy-2,2'-bis(diphenylphosphino)-1,1'-biphenyl; In N,N-dimethyl-formamide; at 100 ℃; for 1h; Inert atmosphere;

(S)-α-methyl-1H-benzimidazole-2-methanamine; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;

upstream raw materials:

(+)-(5,5'-dichloro-6,6'-dimethoxybiphenyl-2,2'-diyl)-bis(diphenylphosphine oxide)

Downstream raw materials:

C₄₈H₃₇Cl₂IrN₂O₈P₂