185949-83-1

Basic information

• Product Name: Propanamide, N-(2,4-difluorophenyl)-
• Synonyms: N-(2,4-difluorophenyl)propanamide
• CAS NO: 185949-83-1
• Molecular Formula: C9H9F2NO
• Molecular Weight: 185.1706664
• Mol File: 185949-83-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Propanamide, N-(2,4-difluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-(2,4-difluorophenyl)-(185949-83-1)
• EPA Substance Registry System: Propanamide, N-(2,4-difluorophenyl)-(185949-83-1)

Safety Data

• Hazardous Substances Data: 185949-83-1(Hazardous Substances Data)

Upstream product

• 367-25-9 2,4-difluorophenylamine 
• 123-62-6 propionic acid anhydride 

Relevant articles and documents

Chemoselective acylation of amines in aqueous media

Amines are efficiently acylated by both cyclic and acyclic anhydrides by dissolving them in an aqueous medium with the help of a surfactant, sodium dodecyl sulfate (SDS). Cyclic and acyclic anhydrides react with equal ease with an amine, and amines with various stereo-electronic factors react at the same rates with an anhydride. Chemoselective acylation of amines in the presence of phenols and thiols and of thiols in the presence of phenols has been achieved. No acidic or basic reagents are used during the reaction. No Chromatographic separation is required for isolation of the acylated products. Reactions in a neutral aqueous medium, easy isolation of products, and innocuous by-products make the present method a green chemical process. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

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