186203-81-6

Basic information

• Product Name: 6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester
• Synonyms: 6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester;6-Boc-octahydropyrrolo[3,4-b]pyridine;(1H-tetrazol-5-yl)MethanaMine hydrochloride;6-Boc-6H-octahydro-pyrrolo[3,4-b]pyridine;tert-butyl (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine-6-carboxylate;tert-Butyl hexahydro-1H-pyrrolo[3,4-b]pyridine-6(2H)-carboxylate;Octahydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylic acid 1,1-dimethylethyl ester;tert-butyl octahydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate
• CAS NO: 186203-81-6
• Molecular Formula: C12H22N2O2
• Molecular Weight: 226.31528
• Mol File: 186203-81-6.mol

Chemical Properties

• Boiling Point: 313.8±15.0 °C(Predicted)
• Appearance: /
• Density: 1.052±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 10.85±0.20(Predicted)
• CAS DataBase Reference: 6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester(186203-81-6)
• EPA Substance Registry System: 6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester(186203-81-6)

Safety Data

• RIDADR: UN3077
• Hazardous Substances Data: 186203-81-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential biological activity and pharmacological properties. Its unique structure allows it to be a promising candidate for the development of new drugs with novel mechanisms of action.
Used in Medicinal Research:
In the field of medicinal research, 6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester serves as a valuable tool for studying the structure-activity relationships of various drug candidates. Its unique chemical properties enable researchers to explore its potential interactions with biological targets, contributing to the advancement of drug discovery and development.
Used in Drug Design and Optimization:
6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester is utilized in drug design and optimization processes to improve the pharmacokinetic and pharmacodynamic profiles of drug candidates. Its unique structural features can be exploited to enhance the potency, selectivity, and safety of new therapeutic agents.
Used in Chemical Synthesis:
In the realm of chemical synthesis, 6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester is employed as a versatile building block for the creation of diverse chemical libraries. Its reactivity and functional groups make it suitable for various synthetic transformations, facilitating the exploration of novel chemical space for potential drug leads.
Used in Biochemical Assays and Screening:
6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester is utilized in biochemical assays and high-throughput screening campaigns to identify and evaluate its potential as a modulator of specific biological targets. Its unique chemical properties allow it to be a valuable probe for understanding the mechanisms of action and potential therapeutic applications in various disease states.
Overall, 6H-Pyrrolo[3,4-b]pyridine-6-carboxylic acid, octahydro-, 1,1-diMethylethyl ester is a versatile and promising compound with a wide range of applications in the pharmaceutical and research industries, driven by its unique structure, potential biological activity, and diverse uses in drug development and chemical synthesis.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 147739-88-6 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine 
• 1059172-92-7 tert-butyl 5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate 

Downstream Products

• 1438082-78-0 tert-butyl 1-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)hexahydro-1H-pyrrolo[3,4-b] pyridine-6(2H)-carboxylate 
• 1438073-32-5 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)propoxy)quinazolin-4-amine 
• 1438073-38-1 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(6-methyloctahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)propoxy)quinazolin-4-amine 

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