18664-78-3

Basic information

• Product Name: 3-AMINO-PENTANOIC ACID
• Synonyms: 3-AMINOVALERIC ACID;3-Aminopentanoic acid;Pentanoic acid, 3-amino-
• CAS NO: 18664-78-3
• Molecular Formula: C₅H₁₁NO₂
• Molecular Weight: 117.15
• Mol File: 18664-78-3.mol

Chemical Properties

• Boiling Point: 230.142 °C at 760 mmHg
• Flash Point: 92.987 °C
• Appearance: /
• Density: 1.067 g/cm³
• Vapor Pressure: 0.024mmHg at 25°C
• Refractive Index: 1.464
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: pK1: 4.02(+1);pK2: 10.399(0) (25°C)
• CAS DataBase Reference: 3-AMINO-PENTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-PENTANOIC ACID(18664-78-3)
• EPA Substance Registry System: 3-AMINO-PENTANOIC ACID(18664-78-3)

Safety Data

• Hazardous Substances Data: 18664-78-3(Hazardous Substances Data)

Usage

Uses

Used in Sports Nutrition:
3-Amino-pentanoic acid is used as a dietary supplement for enhancing athletic performance and endurance. It contributes to the synthesis of carnosine, which helps delay the onset of muscle fatigue during exercise, thereby improving physical performance.
Used in Exercise Physiology Research:
In the field of exercise physiology, 3-AMINO-PENTANOIC ACID is used as a research subject to study its effects on muscle fatigue, athletic performance, and endurance. This research aims to understand the underlying mechanisms of how beta-alanine influences physical performance and to develop strategies for optimizing sports nutrition.
Used in Dietary Sources:
3-Amino-pentanoic acid can be found in various dietary sources such as meat, fish, and poultry. It is used as a natural component in these foods to support the body's protein synthesis and carnosine production, contributing to overall health and physical performance.
Overall, 3-amino-pentanoic acid, or beta-alanine, is an essential component in the body's biochemistry with potential applications in sports nutrition, exercise physiology, and as a natural constituent in various dietary sources. Its role in reducing muscle fatigue and improving athletic performance makes it a valuable asset in the field of sports and fitness.

InChI:InChI=1/C5H11NO2/c1-2-4(6)3-5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

Upstream product

• 141-82-2 malonic acid 
• 123-38-6 propionaldehyde 
• 13991-37-2 trans-2-pentenoic acid 
• 5303-67-3 4-ethylazetidin-2-one 
• 13268-89-8 3-ethyl-4-oxo-valeric acid ethyl ester 

Downstream Products

• 105902-74-7 3-benzoylamino-valeric acid 
• 1086106-67-3 3-(4-fluoro-benzylamino)-pentanoic acid methyl ester 
• 16753-07-4 N-Acryloyl-beta-alanine 
• 159391-69-2 (5S,6S)-6-Ethyl-5-methyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 
• 159391-70-5 (5R,6S)-6-Ethyl-5-methyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 
• 159391-58-9 (S)-6-Ethyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 
• 159391-57-8 (R)-6-Ethyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Preparation of highly enantiopure β-amino esters by Candida antarctica lipase A

The enantioselectivities for the reactions of aliphatic β-substituted β-amino esters [RCH(NH2)CH2CO2Et with R = Me, Et, n-Pr, i-Pr, CHEt2, cyclohexyl and Ph] with butyl butanoate in neat butyl butanoate and with 2,2,2-trifluoroethyl butanoate in diisopropyl ether were studied in the presence of Candida antarctica lipase A. Enantioselectivities ranging from good (E = 70-100) to excellent (E>100) were commonly observed, allowing gram-scale resolution of the substrates.

Highly diastereoselective alkylation of perhydropyrimidin-4-ones directed toward the synthesis of α-substituted β-amino acids. 2

The alkylation of several enantiomerically pure perhydropyrimidin-4-ones at C5 is described. For the methylation reaction, mixtures of 5,6-trans -and cis-disubstituted adducts were obtained with high diastereomeric ratios, whereas only the 5,6-