16753-07-4

Upstream product

• 814-68-6 acryloyl chloride 
• 107-95-9 3-amino propanoic acid 
• 18664-78-3 3-aminopentanoic acid 
• 79-10-7 acrylic acid 

Downstream Products

• 63406-12-2 acrylamido-3 N-benzyl propanamide 
• 219797-98-5 3-Acryloylamino-propionic acid pentafluorophenyl ester 
• 65500-82-5 (acrylamido-3 propionamido)-3 N-benzyl propanamide 
• 65500-84-7 (acrylamido-3 propanamido)-3 N-phenyl propanamide 

Relevant academic research and scientific papers

Synthesis of amino acid-based polymers via atom transfer radical polymerization in aqueous media at ambient temperature

Well-defined acryloyl β-alanine (ABA) polymers were synthesized directly via atom transfer radical polymerization (ATRP) under near physiological conditions using various water soluble initiators with high yield and narrow molecular weight distributions. The Royal Society of Chemistry 2005.

Synthesis of new cotelomers derived from tris(hydroxymethyl) aminomethane bearing arabinofuranosylcytosine moieties. Preliminary results on their in vitro and in vivo antitumoral activities

As an approach to the development of drug delivery systems, a new class of low macromolecular carriers called telomers bearing both antitumor agent such as arabinofuranosylcytosine (Ara-C) and galactose moieties were synthesized. These compounds were prep

Cooperativity of Catechols and Amines in High-Performance Dry/Wet Adhesives

The outstanding adhesive performance of mussel byssal threads has inspired materials scientists over the past few decades. Exploiting the amino-catechol synergy, polymeric pressure-sensitive adhesives (PSAs) have now been synthesized by copolymerizing tra

Stimulus-responsive compd., deformable polymer, deformable material and actuator (by machine translation)

PROBLEM TO BE SOLVED: large displacement at low voltage which can provide a stimulus compd., large displacement at low voltage, it is possible to provide a deformation resistance, large displacement at low voltage to provide a deformable material which can, in addition, can be greatly displaced in the low voltage to the actuator. SOLUTION: the present invention responsiveness compd., functions as a rotary shaft having a coupling, and, the coupling of the first and located at one end of the base 1, 2 of the coupling and the other end of the unit having a first position A and a base, the base of the first coupling part 1 1 1 B and disposed on the second unit, the base of the first portion of the first coupling 2 2 2 disposed on the second unit B and having a, 1 2 of the first unit to the second unit B and B are, respectively, having an electron-donating group has a structure orthobenzenedithiols, coupled to each other by oxidation-reduction reaction and in which. Selected drawing: no (by machine translation)

Novel 3-hydroxypyridin-4-one hexadentate ligand-based polymeric iron chelator: Synthesis, characterization and antimicrobial evaluation

A novel 3-hydroxypyridin-4-one (HPO) hexadentate monomeric chelator 14 has been synthesized and incorporated into polymers by copolymerization with 2-hydroxyethyl acrylate (HEA), using azobisisobutyronitrile (AIBN) as an initiator. The monomeric chelator was found to possess very high affinity for iron(III), with the log stability constant of the iron complex (log K1) = 33.61 and pFe3+ = 30.37. The iron binding capacity and monomer recovery of the copolymers were determined using spectrophotometry. The in vitro antimicrobial activity of monomeric chelator 14 and polymeric chelator 16-4 against both Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) and Gram-negative bacteria (Escherichia coli, Salmonella spp., and Pseudomonas aeruginosa) was evaluated by inhibition zone and minimum inhibitory concentration (MIC) assays, which demonstrated that both monomeric and polymeric chelators possess inhibitory activity. The polymeric chelators possess potential application for the treatment of wound infection.

MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME

The present invention relates to ionic silicone hydrogel polymers comprising at least one pharmaceutical or nutriceutical component and displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake.

Synthesis of cotelomers derived from tris(hydroxymethyl)acrylamidomethane (THAM) bearing cytosine arabinoside moieties. Preliminary investigation of their biological activity

The telomerization of tris(hydroxymethyl)acrylamidomethane (THAM) and cytosine arabinoside (Ara-C) polymerizable derivatives in the presence of transfer reagent such as alkane or perfluoroalkane thiol is described. The cytotoxic activities of these differ

Water soluble polymers containing amino acid residues for dental restoratives

Glass ionomer cements for dental restoratives with improved physical properties are produced by the present invention. Acryloyl and methacryloyl derivatives of amino acids are used in the invention to copolymerize with acrylic acid, methacrylic acid or various acrylic acid-comonomer mixtures to produce water soluble polycarboxylic acids.

Polymeric iron chelators

The present invention relates to polymeric iron chelators based upon hydroxamic acids having the general formula: STR1 wherein R is hydrogen or lower alkyl. The present compound is useful for the treatment of iron overload disorders particularly arising from iron poisoning and the disease β-thalassemia otherwise known as Cooley's Anemia. The polymeric hydroxamic acids of the present invention exhibit high selectivity for iron, good water solubility for both the chelator and its iron complex, low toxicity and, most significantly, increased bioactivity, i.e., the ability to remove iron in vivo.

Synthese et proprietes de monomeres acryliques porteurs d'un groupement fonctionnel acylant. Preparation d'un nouveau copolymere acylant pour l'immobilisation des biomolecules

Carboxylic acids bearing an ω-acrylamido group were reacted with mercaptothiazoline in the presence of DCC to give the corresponding N-acyl thiazolidin-2-thiones (3 - 5) in good yields.On treatment with benzylamine, piperidine or aniline, these acyl deriv