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CAS

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187324-63-6

(1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

187324-63-6 Suppliers

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  • 187324-63-6 Structure

  • Basic information

    1. Product Name: (1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL
    2. Synonyms: (1R,2S)-2-[N-BENZYL-N-(2,4,6-TRIMETHYLBENZENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL;(1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL;(1R,2S)-N-BENZYL-N-(MESITYLENESULFONYL)NOREPHEDRINE;(1R,2S)-Benzylmesitylenesulfonylaminophenylpropanol;(1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL 97+%;N-Benzyl-1-(3,5-dimethylphenyl)-N-((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)methanesulfonamide;(1R,2S)-N-Benzyl-N-(mesitylenesulfonyl)norephedrine (1R,2S)-2-[N-Benzyl-N-(2,4,6-trimethylbenzenesulfonyl)amino]-1-phenyl-1-propanol;BenzenesulfonaMide,N-[(1S,2R)-2-hydroxy-1-Methyl-2-phenylethyl]-2,4,6-triMethyl-N-(phenylMethyl)-
    3. CAS NO:187324-63-6
    4. Molecular Formula: C25H29NO3S
    5. Molecular Weight: 423.57
    6. EINECS: N/A
    7. Product Categories: Asymmetric Synthesis;Synthetic Organic Chemistry
    8. Mol File: 187324-63-6.mol

  • Chemical Properties

    1. Melting Point: 130.0 to 134.0 °C
    2. Boiling Point: 601.9oC at 760 mmHg
    3. Flash Point: 317.8oC
    4. Appearance: /
    5. Density: 1.186g/cm3
    6. Vapor Pressure: 2.45E-15mmHg at 25°C
    7. Refractive Index: -7 ° (C=2, CHCl3)
    8. Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
    9. Solubility: N/A
    10. PKA: 13.49±0.20(Predicted)
    11. CAS DataBase Reference: (1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL(CAS DataBase Reference)
    12. NIST Chemistry Reference: (1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL(187324-63-6)
    13. EPA Substance Registry System: (1R,2S)-2-[N-BENZYL-N-(MESITYLENESULFONYL)AMINO]-1-PHENYL-1-PROPANOL(187324-63-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 187324-63-6(Hazardous Substances Data)

187324-63-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 187324-63-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,3,2 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 187324-63:
(8*1)+(7*8)+(6*7)+(5*3)+(4*2)+(3*4)+(2*6)+(1*3)=156
156 % 10 = 6
So 187324-63-6 is a valid CAS Registry Number.
InChI:InChI=1/C25H29NO3S/c1-18-15-19(2)25(20(3)16-18)30(28,29)26(17-22-11-7-5-8-12-22)21(4)24(27)23-13-9-6-10-14-23/h5-16,21,24,27H,17H2,1-4H3/t21-,24-/m0/s1

187324-63-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N-benzyl-N-[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]-2,4,6-trimethylbenzenesulfonamide

1.2 Other means of identification

Product number -
Other names (1R,2S)-2-[N-Benzyl-N-(2,4,6-trimethylbenzenesulfonyl)amino]-1-phenyl-1-propanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:187324-63-6 SDS

187324-63-6Relevant articles and documents

Modular total synthesis of archazolid A and B

Menche, Dirk,Hassfeld, Jorma,Li, Jun,Mayer, Kerstin,Rudolph, Sven

supporting information; experimental part, p. 7220 - 7229 (2010/02/17)

(Chemical Equation Presented) A modular total synthesis of the potent V-ATPase inhibitors archazolid A and B is reported. The convergent preparation was accomplished by late-stage diversification of joint intermediates. Key synthetic steps involve asymmetric boron-mediated aldol reactions, two consecutive Still-Gennari olefinations to set the characteristic (Z,Z)-diene system, a Brown crotyboration, and a diastereo-selective aldol condensation of highly elaborate intermediates. For macrocyclization, both an HWE reaction and a Heck coupling were successfully employed to close the 24-membered macrolactone. During the synthetic campaign, a generally useful protocol for an E-selective Heck reaction of nonactivated alkenes and a method for the direct nucleophilic displacement of the Abiko-Masamune auxiliary with sterically hindered nucleophiles were developed. The expedient and flexible strategy will enable further SAR studies of the archazolids and more detailed evaluations of target-inhibitor interactions. 2009 American Chemical Society.

Boron-mediated aldol reaction of carboxylic esters: Complementary anti- and syn-selective asymmetric aldol reactions

Inoue, Tadashi,Liu, Ji-Feng,Buske, Dana C.,Abiko, Atsushi

, p. 5250 - 5256 (2007/10/03)

The boron-mediated aldol reaction of carboxylic esters is described in detail. Contrary to the general belief that carboxylic esters are inert under the condition of the boron enolate formation, propionate esters are enolized with certain combinations of a boron triflate and an amine. More importantly, the stereochemical course of the aldol reaction can be controlled by the judicious selection of the enolization reagents. Treatment of propionate esters with c-Hex2BOTf and triethylamine produces anti-aldol products, and that with Bu2BOTf and diisopropylethylamine gives syn-aldol products selectively after reaction with aldehydes. Complementary anti- and syn-selective asymmetric aldol reactions with structurally related, readily available chiral norephedrine-derived propionate esters are developed.