188707-99-5Relevant articles and documents
NOVEL OXAZOLE DERIVATIVES THAT INHIBIT SYK
-
Paragraph 0104, (2017/04/04)
The present invention is concerned with substituted oxazole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human and animal diseases s
Silver catalysed decarboxylative alkylation and acylation of pyrimidines in aqueous media
Mai, Wen-Peng,Sun, Bin,You, Li-Qin,Yang, Liang-Ru,Mao, Pu,Yuan, Jin-Wei,Xiao, Yong-Mei,Qu, Ling-Bo
, p. 2750 - 2755 (2015/04/21)
Decarboxylative alkylation or acylation reactions of simple pyrimidines have been developed in aqueous media. Using aliphatic carboxylic acids or 2-oxocarboxylic acids and pyrimidines as substrates and silver as the catalyst, the 4-substituted alkyl or ac
DIAZASPIROALKANEONE-SUBSTITUTED OXAZOLE DERIVATIVES AS SPLEEN TYROSINE KINASE INHIBITORS
-
Page/Page column 39, (2015/12/08)
The present invention is concerned with diazaspiroalkanone- substituted oxazole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human a
Efficient discovery of potent anti-HIV agents targeting the Tyr181Cys variant of HIV reverse transcriptase
Jorgensen, William L.,Bollini, Mariela,Thakur, Vinay V.,Domaoal, Robert A.,Spasov, Krasimir A.,Anderson, Karen S.
supporting information; experimental part, p. 15686 - 15696 (2011/12/03)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) that interfere with the replication of human immunodeficiency virus (HIV) are being pursued with guidance from molecular modeling including free-energy perturbation (FEP) calculations for protein-in
Trialkylalanes in palladium-catalyzed C-alkylations of azines
Lu, Qingbo,Mangalagiu, Lonel,Benneche, Tore,Undheim, Kjell
, p. 302 - 306 (2007/10/03)
Carbo-substitution with alkyl groups in halogenoazines is readily effected under the influence of Pd-catalysis with alanes as the donor of the alkyl group. Acta Chemica Scandinavica 1997.
Pyri(mi)dyl-oxy-and -thio-benzoic acid derivatives useful as herbicides and plant growth regulants
-
, (2008/06/13)
New pyri(mi)dyl-oxy- or -thio-benzoic acid derivatives of the formula STR1 are taught which have herbicidal and plant growth regulating activity. In the formula Z can be Ch or N, X is oxygen or sulphur, A is oxygen, sulphur, a radical R5 --N=or a radical R6 O--N=and B is oxygen, sulphur, a radical STR2 with the proviso that at least one of the radicals R1, R2 or R3 represents alkyl or a part of a 3- to 6-membered fused carbocyclic ring.