188916-67-8

Basic information

• Product Name: (S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone
• Synonyms: (S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone;[(3S)-3-(3,4-Dichlorophenyl)-3-(3-iodopropyl)-1-piperidinyl]phenylmethanone;Methanone, [(3S)-3-(3,4-dichlorophenyl)-3-(3-iodopropyl)-1-piperidinyl]phenyl-;Piperidine, 1-benzoyl-3-(3,4-dichlorophenyl)-3-(3-iodopropyl)-, (3S)-;[(3S)-3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl]-phenylmethanone
• CAS NO: 188916-67-8
• Molecular Formula: C₂₁H₂₂Cl₂INO
• Molecular Weight: 502.22
• Mol File: 188916-67-8.mol

Chemical Properties

• Appearance: /
• Density: 1.503
• CAS DataBase Reference: (S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone(188916-67-8)
• EPA Substance Registry System: (S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone(188916-67-8)

Safety Data

• Hazardous Substances Data: 188916-67-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone is used as an organic synthesis intermediate for the preparation of various complex organic molecules. Its unique structure allows it to serve as a building block in the creation of a wide range of chemical entities, including those with potential applications in materials science, pharmaceuticals, and other specialized fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone is used as a pharmaceutical intermediate. It plays a crucial role in the development of new drugs and active pharmaceutical ingredients (APIs). Its presence in the molecular structure of final drug products can contribute to their therapeutic effects, pharmacokinetics, and safety profiles.
Used in Laboratory Research and Development:
(S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone is also employed in laboratory research and development processes. Researchers use this compound to explore its chemical reactivity, investigate its potential applications, and study its interactions with other molecules. This research can lead to the discovery of new chemical reactions, the development of novel synthetic routes, and the creation of new compounds with specific properties.
Used in Chemical Production Process:
Finally, (S)-(3-(3,4-dichlorophenyl)-3-(3-iodopropyl)piperidin-1-yl)(phenyl)methanone is utilized in the chemical production process. It is an essential component in the synthesis of various chemicals, which may be used in a wide range of applications, from industrial materials to consumer products. Its presence in these processes ensures the production of high-quality chemical products that meet the required specifications and performance standards.

Upstream product

• 172734-71-3 (+)-3(S)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-(3-methanesulphonyloxypropyl)piperidine 
• 172734-70-2 (S)-(3-(3,4-dichlorophenyl)-3-(3-hydroxypropyl)piperidin-1-yl)(phenyl)methanone 

Downstream Products

• 172734-92-8 osanetant 

Relevant articles and documents

A practical and scalable synthesis of SR 142801, a tachykinin NK3 antagonist

A practical and scalable total synthesis of tachykinin NK3 receptor antagonist SR 142801, (R)-N-[1-[3-[1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4 -piperidinyl]-N-methyl acetamide 1 is described. The absolute configuration of the key intermediate 7 was determined by single crystal X-ray crystallography, on the basis of which, the absolute configuration of SR 142801 should be (R)-(+), instead of the recently reported (S)-(+).