- Selective reduction of 2,4-dinitro- and 4,5-dinitroimidazole derivatives using iron dust
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(Chemical Equation Presented) A series of N-substituted 2,4-dinitroimidazoles, 4,5-dinitroimidazoles, and 2-methyl-4,5-dinitroimidazoles have been selectively reduced to the corresponding aminonitroimidazole derivatives, using iron dust in glacial acetic acid at room temperature. 2,4-Dinitroimidazoles have been reduced to the 2-amino-4-nitro-derivatives only but 4,5-dinitroimidazoles have given 4-amino-5-nitro- or 5-amino-4- nitroderivatives depended on the structure of the N-substituent.
- Olender, Dorota,Zwawiak, Justyna,Zaprutko, Lucjusz
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scheme or table
p. 1049 - 1055
(2010/10/21)
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- NITROIMIDAZOLES. PART V. CHLORONITROIMIDAZOLES FROM DINITROIMIDAZOLES. A REINVESTIGATION
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5(4)-Chloro-4(5)-nitroimidazole and 2-chloro-4(5)-nitroimidazole or their N-methyl derivatives have been synthesized in at least two independent routes.In contrast to some former reports it has been established that from 2,4(or 5)-dinitroimidazoles only 2-chloro-4(or 5)-nitroimidazoles are obtained.In 4,5-dinitroimidazoles only a nitro group in the 5-position is replaced by a chlorine atom.Structures of the obtained compounds have been confirmed by analyses of physico-chemical data.
- Suwinski, Jerzy,Salwinska, Ewa,Watras, Jan,Widel, Maria
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p. 1261 - 1272
(2007/10/02)
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