Selective binding of TAR RNA by a Tat-derived β-peptide
(Equation presented) The interaction between the HIV-1 Tat protein and the TAR RNA element in the nascent viral genomic transcript is required for viral replication. An 11-residue β-peptide (1), an all-β homologue of the Arg-rich region Tat 47-57, binds T
Gelman, Michael A.,Richter, Sara,Cao, Hong,Umezawa, Naoki,Gellman, Samuel H.,Rana, Tariq M.
A Facile Approach for Synthesis and Intracellular Delivery of Size Tunable Cationic Peptide Functionalized Gold Nanohybrids in Cancer Cells
Peptide-based drug delivery systems have become a mainstay in the contemporary medicinal field, resulting in the design and development of better pharmaceutical formulations. However, most of the available reports employ tedious multiple reaction steps fo