Novel inhibitors of carboxypeptidase G2 (CPG2): Potential use in antibody-directed enzyme prodrug therapy
The design and synthesis of potent thiocarbamate inhibitors for carboxypeptidase G2 are described. The best thiocarbamate inhibitor N-(p- methoxybenzenethiocarbonyl)amino-L-glutamic acid 6d, chosen for preliminary investigations of in vitro ant
Khan, Tariq H.,Eno-Amooquaye, Ebun A.,Searle, Frances,Browne, Pat J.,Osborn, Helen M. I.,Burke, Philip J.