19241-18-0 Usage
Uses
Used in Organic Synthesis:
2,4,5-Trimethylphenyl isothiocyanate is used as a key intermediate in the synthesis of various organic compounds for applications in the pharmaceutical and agrochemical industries. Its unique chemical structure allows for the creation of a wide range of products with diverse therapeutic and pesticidal properties.
Used in Biomolecule Modification:
2,4,5-TRIMETHYLPHENYL ISOTHIOCYANATE is employed as a reagent for the modification of biomolecules, enabling researchers to study the structure, function, and interactions of these molecules in biological systems. The isothiocyanate group in 2,4,5-Trimethylphenyl isothiocyanate can react with nucleophilic groups present in biomolecules, facilitating the attachment of various functional groups for further analysis and application.
Used in Enzymatic Reaction Studies:
2,4,5-Trimethylphenyl isothiocyanate is utilized in the study of enzymatic reactions, providing insights into the mechanisms of enzyme-catalyzed processes. Its ability to act as a substrate or inhibitor in enzymatic reactions aids in understanding the role of enzymes in various biological pathways and their potential as therapeutic targets.
Used in Environmental Monitoring:
Due to its potential environmental hazards, 2,4,5-Trimethylphenyl isothiocyanate is also used in monitoring programs to assess its presence and impact on air, water, and soil quality. This helps in the development of strategies to minimize its release into the environment and mitigate its effects on ecosystems and human health.
Check Digit Verification of cas no
The CAS Registry Mumber 19241-18-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,4 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19241-18:
(7*1)+(6*9)+(5*2)+(4*4)+(3*1)+(2*1)+(1*8)=100
100 % 10 = 0
So 19241-18-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NS/c1-7-4-9(3)10(11-6-12)5-8(7)2/h4-5H,1-3H3
19241-18-0Relevant articles and documents
Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors
Wilson, Kenneth J.,Illig, Carl R.,Subasinghe, Nalin,Hoffman, James B.,Jonathan Rudolph,Soll, Richard,Molloy, Christopher J.,Bone, Roger,Green, David,Randall, Troy,Zhang, Marie,Lewandowski, Frank A.,Zhou, Zhao,Sharp, Celia,Maguire, Diane,Grasberger, Bruce,DesJarlais, Renee L.,Spurlino, John
, p. 915 - 918 (2007/10/03)
The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is described. Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities.
