193469-44-2

Basic information

• Product Name: 2-BENZYL-PIPERIDIN-4-ONE
• Synonyms: 2-BENZYL-PIPERIDIN-4-ONE;2-Benzyl-4-piperidinone HCl;4-Piperidinone,2-(phenylmethyl)-
• CAS NO: 193469-44-2
• Molecular Formula: C₁₂H₁₅NO
• Molecular Weight: 189.25
• Mol File: 193469-44-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-BENZYL-PIPERIDIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYL-PIPERIDIN-4-ONE(193469-44-2)
• EPA Substance Registry System: 2-BENZYL-PIPERIDIN-4-ONE(193469-44-2)

Safety Data

• Hazardous Substances Data: 193469-44-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-BENZYL-PIPERIDIN-4-ONE is used as an intermediate in the synthesis of various pharmaceuticals due to its unique chemical structure and properties, contributing to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
2-BENZYL-PIPERIDIN-4-ONE is utilized as an intermediate in the production of agrochemicals, specifically for the development of insecticides and herbicides, leveraging its insecticidal and herbicidal activities to control pests and weeds in agricultural settings.
Used in Central Nervous System Research:
2-BENZYL-PIPERIDIN-4-ONE is employed as a research compound for exploring its potential as a central nervous system agent, with the aim of discovering its effects on neurological functions and disorders.
Used in Anti-Inflammatory and Analgesic Applications:
2-BENZYL-PIPERIDIN-4-ONE is studied for its potential anti-inflammatory and analgesic properties, suggesting that it may be used in the development of medications to alleviate pain and reduce inflammation in various conditions.
Further research is necessary to fully understand the scope of 2-BENZYL-PIPERIDIN-4-ONE's applications and effects, ensuring its safe and effective use across different industries.

Upstream product

• 193201-63-7 (±)-7-(phenylmethyl)-1,4-dioxa-8-azaspiro[4.5]decane 

Downstream Products

• 190964-86-4 (+/-)-1-[3,5-bis-(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinone 
• 193480-28-3 (+/-)-1,1-dimethylethyl 4-oxo-2-(phenylmethyl)-1-piperidinecarboxylate 
• 190964-85-3 (+/-)-1-((3,5)-dimethylbenzoyl)-2-(phenylmethyl)-4-piperidinone 

Relevant articles and documents

1-(1,2-disubstituted pipeidinyl)-4-substituted piperidine derivatives

The present invention concerns compounds of formula the N-oxide forms, the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein n is 0, 1 or 2; m is 1 or 2, provided that if m is 2, then n is 1; p is 0, 1 or 2; ═Q is ═O or ═NR3; X is a covalent bond or a bivalent radical of formula —O—, —S—, —NR3—; R1is Ar1; Ar1C1-6alkyl or di(Ar1)C1-6alkyl, wherein each C1-6alkyl group is optionally substituted with hydroxy, C1-4alkyloxy, oxo or a ketalized oxo substituent of formula —O—CH2—CH2—O— or —O—CH2—CH2—CH2—O—; R2is Ar2; Ar2C1-6alkyl; Het or HetC1-6alkyl; R3is hydrogen or C1-6alkyl; R4is hydrogen; C1-4alkyl; C1-4alkyloxyC1-4alkyl; hydroxyC1-4alkyl; carboxyl; C1-4alkyloxycarbonyl or Ar3; R5is hydrogen; hydroxy; Ar3; Ar3C1-6alkyloxy; di(Ar3)C1-6alkyloxy; Ar3C1-6alkylthio; di(Ar3)C1-6alkylthio; Ar3C1-6alkylsulfoxy; di(Ar3)C1-6alkylsulfoxy; Ar3C1-6alkylsulfonyl; di(Ar3)C1-6alkylsulfonyl; —NR7R8; C1-6alkyl substituted with —NR7R8; or a radical of formula (a-1) or (a-2); R4and R5may also be taken together; R6is hydroxy; C1-6alkyloxy; C1-6alkyl or Ar3C1-6alkyl; Ar1, Ar2and Ar3are phenyl or substituted phenyl; Ar2is also naphtalenyl; and Het is an optionally substituted monocyclic or bicyclic heterocycle; as substance P antagonists; their preparation, compositions containing them and their use as a medicine.

1-(1,2-disubstituted piperidinyl)-4 (fused imidazole)-piperidine derivatives

This invention concerns the compounds of formula the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein n is 0, 1 or 2; m is 1 or 2, provided that if m is 2, then n is 1; ═Q is ═O or ═NR

1-(1,2-Disubstituted piperidinyl)-4-substituted piperidine derivatives

The present invention concerns compounds of formula the N-oxide forms, the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein n is 0, 1 or 2; m is 1 or 2, provided that if m is 2, then n is 1; p is 0, 1 or 2; =