195984-91-9 Usage
Uses
Used in Pharmaceutical Industry:
(R)-1-((1H-iMidazol-5-yl)Methyl)-3-benzyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-7-carbonitrile is used as a potential therapeutic agent for various conditions due to its structural similarity to benzodiazepines. Its application is based on the expectation that it may provide sedative, anxiolytic, and muscle relaxant effects.
Used in Chemical Synthesis:
In the chemical industry, (R)-1-((1H-iMidazol-5-yl)Methyl)-3-benzyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-7-carbonitrile is used as a precursor compound for the synthesis of other complex molecules. The presence of the carbonitrile group allows for further chemical reactions, making it a versatile building block in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 195984-91-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,9,8 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 195984-91:
(8*1)+(7*9)+(6*5)+(5*9)+(4*8)+(3*4)+(2*9)+(1*1)=209
209 % 10 = 9
So 195984-91-9 is a valid CAS Registry Number.
195984-91-9Relevant articles and documents
Discovery of (R)-7-cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4- (2-thienysulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a farnesyltransferase inhibitor with potent preclinical antitumor activity
Hunt,Ding,Batorsky,Bednarz,Bhide,Cho,Chong,Chao,Gullo-Brown,Guo,Soong Hoon Kim,Lee,Leftheris,Miller,Mitt,Patel,Penhallow,Ricca,Rose,Schmidt,Slusarchyk,Vite,Manne
, p. 3587 - 3595 (2007/10/03)
Continuing structure-activity studies were performed on the 2,3,4,5-tetrahydro-1-(imidazol-4-ylalkyl)-1,4-benzodiazepine farnesyltransferase (FT) inhibitors. These studies demonstrated that a 3(R)-phenylmethyl group, a hydrophilic 7-cyano group, and a 4-s
