19701-84-9

Basic information

• Product Name: AC-VAL-NHME
• Synonyms: ACETYL-L-VALINE METHYL AMIDE;AC-VALINE-NHME;AC-VAL-NHME;N-ALPHA-ACETYL-L-VALINE METHYL AMIDE
• CAS NO: 19701-84-9
• Molecular Formula: C8H16N2O2
• Molecular Weight: 172.22
• Mol File: 19701-84-9.mol

Chemical Properties

• Melting Point: >250 °C (sublm)(Solv: ethyl acetate (141-78-6))
• Boiling Point: 402°C at 760 mmHg
• Flash Point: 180.4°C
• Appearance: /
• Density: 0.994g/cm³
• Vapor Pressure: 1.14E-06mmHg at 25°C
• Refractive Index: 1.446
• Storage Temp.: Store at RT.
• PKA: 14.54±0.46(Predicted)
• CAS DataBase Reference: AC-VAL-NHME(CAS DataBase Reference)
• NIST Chemistry Reference: AC-VAL-NHME(19701-84-9)
• EPA Substance Registry System: AC-VAL-NHME(19701-84-9)

Safety Data

• Hazardous Substances Data: 19701-84-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
AC-VAL-NHME is used as a research compound for the synthesis of peptides and proteins with specific structural and functional properties. Its unique modification can potentially enhance the stability, solubility, or activity of the resulting biomolecules, contributing to the development of novel therapeutic agents.
Used in Biochemical Studies:
In the field of biochemistry, AC-VAL-NHME is utilized to investigate the role of amino acid modifications in biological processes. By studying the effects of the N-methyl group on the amino acid's interactions and biological activity, researchers can gain insights into the mechanisms underlying protein function and regulation.
Used in Drug Design and Development:
AC-VAL-NHME is employed as a building block in the design and development of new drugs. Its unique properties can be leveraged to create molecules with improved pharmacokinetic and pharmacodynamic profiles, leading to more effective and safer therapeutics.
Used in Peptide Synthesis:
In the synthesis of peptides, AC-VAL-NHME is used as a modified amino acid to introduce specific structural features or functional groups into the peptide sequence. This can result in peptides with enhanced biological activity, selectivity, or stability, which can be applied in various therapeutic or diagnostic applications.
Used in Protein Engineering:
AC-VAL-NHME is utilized in protein engineering to create proteins with altered properties or novel functions. By incorporating the modified amino acid into the protein sequence, researchers can explore the effects of the N-methyl group on protein folding, stability, and interactions with other biomolecules, paving the way for the development of engineered proteins with improved performance in various applications.

InChI:InChI=1/C8H16N2O2/c1-5(2)7(8(12)9-4)10-6(3)11/h5,7H,1-4H3,(H,9,12)(H,10,11)/t7-/m0/s1

Upstream product

• 96-81-1 N-acetyl-L-valine 
• 74-89-5 methylamine 
• 13734-41-3 t-Boc-L-valine 
• 108-24-7 acetic anhydride 
• 87105-26-8 L-valine N-methylamide 
• 71988-70-0 (S)-2-N-Boc-N,3-dimethylbutanamide 
• 1492-15-5 (S)-N-acetylvaline methyl ester 

Relevant articles and documents

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