Enantioselective butylation of aliphatic aldehydes by mixed chiral lithium amide/n-BuLi dimers
The enantioselective butylation of aliphatic aldehydes with mixtures of n-butyllithium and chiral lithium amides in a diethyl ether-dimethoxymethane solvent mixture is described. Enantiomeric excesses ranging from 91 to 98.5% were observed for several aliphatic alcohols. The asymmetric butylation of the prochiral aldehydes proceeds much faster by the mixed lithium amide/n- BuLi complexes than by tetrameric n-BuLi.
Arvidsson, Per I.,Davidsson, Oejvind,Hilmersson, Goeran
p. 527 - 534
(2007/10/03)
Hydroboration of olefins with catecholborane at room temperature in the presence of N,N-dimethylacetamide
-
Garrett, Christine E.,Fu, Gregory C.
p. 3224 - 3225
(2007/10/03)
More Articles about upstream products of 19781-28-3