198277-06-4

Basic information

• Product Name: 4-BROMO-2-(2-HYDROXYETHYL)PHENOL
• Synonyms: 4-BROMO-2-(2-HYDROXYETHYL)PHENOL;4-bromo-2-(2-hydroxyethyl)phenol(WX191331)
• CAS NO: 198277-06-4
• Molecular Formula: C₈H₉BrO₂
• Molecular Weight: 217.06
• Mol File: 198277-06-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-BROMO-2-(2-HYDROXYETHYL)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-(2-HYDROXYETHYL)PHENOL(198277-06-4)
• EPA Substance Registry System: 4-BROMO-2-(2-HYDROXYETHYL)PHENOL(198277-06-4)

Safety Data

• Hazardous Substances Data: 198277-06-4(Hazardous Substances Data)

Upstream product

• 38692-72-7 2-hydroxy-5-bromo-phenylacetic acid 

Downstream Products

• 1062614-38-3 1-(3-bromo-4-fluorophenyl)-2-(4-(difluoromethoxy)-3-(2-fluoroethyl)phenyl)ethane-1,2-dione 
• 1062614-72-5 2-(2,2-difluoroethoxy)-4-((4-(difluoromethoxy)-3-methylphenyl)ethynyl)-1-fluorobenzene 
• 1062614-35-0 2-bromo-4-((4-(difluoromethoxy)-3-(2-fluoroethyl)phenyl)ethynyl)-1-fluorobenzene 
• 1062614-28-1 ((4-(difluoromethoxy)-3-(2-fluoroethyl)phenyl)ethynyl)trimethylsilane 
• 1062614-31-6 1-(difluoromethoxy)-4-ethynyl-2-(2-fluoroethyl)benzene 
• 1062616-16-3 4-bromo-1-(difluoromethoxy)-2-(2-methoxyethyl)benzene 
• 1062614-03-2 4-bromo-1-(difluoromethoxy)-2-(2-fluoroethyl)benzene 
• 1062614-00-9 2-(5-bromo-2-(difluoromethoxy)phenyl)ethanol 
• 198277-10-0 2-[4-Bromo-2-(2-hydroxy-ethyl)-phenoxy]-malonic acid diethyl ester 

Relevant articles and documents

Aryl-substituted acrylamides with Leukotriene B4 (LTB-4) receptor antagonist activity

Disclosed are compounds of formula (I) wherein W is CH or N; R is (mono- or di cabocyclic or heterocyclic aryl)-lower alkyl; R1is hydrogen or lower alkyl; R2and R3are hydrogen, lower alkyl, lower alkoxy-lower alkyl or aryl

HETEROCYCLIC BETA-ADRENERGIC AGONISTS

The present invention relates to certain compounds of the formula (I) the racemic-enantiomeric mixtures and optical isomers of said compounds and the pharmaceutically acceptable salts or prodrugs thereof, depicted below, which are β-adrenergic receptor agonists and accordingly have utility as, inter alia, hypoglycemic and antiobesity agents. More specifically, the compounds of the instant invention are selective agonists of β 3-adrenergic receptor. The invention also relates to methods of use for the compounds and to pharmaceutical compositions containing them. The compounds of the present invention also possess utility for increasing lean meat deposition and/or improving the lean meat to fat ratio in animals, e.g., ungulate animals, companion animals and poultry. The compounds have the formula STR1 wherein R. sup.1, R. sup.2, R 3, R 4, R 5, Y and Z are as defined in the specification.