19842-08-1

Basic information

• Product Name: 2-BroMo-5-ethylpyridine
• Synonyms: 2-BroMo-5-ethylpyridine
• CAS NO: 19842-08-1
• Molecular Formula: C₇H₈BrN
• Molecular Weight: 186.04912
• Mol File: 19842-08-1.mol

Chemical Properties

• Boiling Point: 120-122℃ (23 Torr)
• Appearance: /
• Density: 1.413±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.14±0.10(Predicted)
• CAS DataBase Reference: 2-BroMo-5-ethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-5-ethylpyridine(19842-08-1)
• EPA Substance Registry System: 2-BroMo-5-ethylpyridine(19842-08-1)

Safety Data

• Hazardous Substances Data: 19842-08-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-BroMo-5-ethylpyridine is used as a key intermediate for the synthesis of biologically active compounds, specifically for the preparation of potential prostacyclin receptor inhibitors. These inhibitors play a crucial role in modulating various physiological processes and have potential applications in the treatment of conditions such as cardiovascular diseases, inflammation, and other related disorders.
In the synthesis of these biologically active compounds, 2-BroMo-5-ethylpyridine serves as a versatile building block, allowing for further functionalization and modification to optimize the pharmacological properties of the resulting molecules. Its unique structural features, including the bromine atom and ethyl group, provide opportunities for various chemical reactions, enabling the development of novel and effective therapeutic agents.

Upstream product

• 536-78-7 3-ethylpyridine 

Downstream Products

• 1207878-24-7 3-(5-ethylpyridin-2-yl)-4-methylaniline 
• 105355-27-9 Pioglitazone 
• 1092938-73-2 methyl (3-{[5-(5-ethylpyridin-2-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxy)acetate 
• 1092938-75-4 (3-{[5-(5-Ethylpyridin-2-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxy)acetic acid 
• 1092938-13-0 tert-Butyl (6R)-6-{[5-(5-ethylpyridin-2-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}heptanoate 

Relevant articles and documents

OSMIUM-CONTAINING REDOX MEDIATOR

A new group of Os(II) and Os(III) compounds useful as redox mediators in electrochemical biosensors is presented. These compounds have 1) low oxidation potential, 2) fast reaction kinetics between the electroactive center of an enzyme and the compound, 3) slow oxidation of osmium by oxygen, and 4) excellent solubility in aqueous medium. The figure shows is a cyclic voltammagram of the compound [Os(III)(bpy)2imCl]Cl2, wherein im is imidazolyl. These mediator compounds are particularly useful as a component of a reagent for measuring analytes from a biological fluid, such as blood.