2-BroMo-5-ethylpyridine

Base Information

• Chemical Name: 2-BroMo-5-ethylpyridine
• CAS No.: 19842-08-1
• Molecular Formula: C7H8BrN
• Molecular Weight: 186.051
• Hs Code.: 2933399090
• Mol file: 19842-08-1.mol

Synonyms:2-bromo-5-ethyl-pyridine;6-Bromo-3-ethylpyridine;

Chemical Property of 2-BroMo-5-ethylpyridine

Chemical Property:

• Boiling Point: 120-122℃ (23 Torr)
• PKA: 1.14±0.10(Predicted)
• PSA: 12.89000
• Density: 1.413±0.06 g/cm3(Predicted)
• LogP: 2.40650
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-5-ethylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-BroMo-5-ethylpyridine is a disubstituted pyridine used in the preparation of biologically active compounds such as potential prostacyclin receptor inhibitors.

Technology Process of 2-BroMo-5-ethylpyridine

There total 3 articles about 2-BroMo-5-ethylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 0.5%

3-ethylpyridine (536-78-7,151103-56-9) → 2-bromo-5-ethylpyridine (19842-08-1) + 4-bromo-3-ethylpyridine (10168-60-2) + 5-bromo-3-ethylpyridine (142337-95-9) + 2-bromo-3-ethylpyridine (142337-94-8) + 2,3-dibromo-5-ethylpyridine (142337-97-1) + 2,5-dibromo-3-ethylpyridine (142337-96-0)

Guidance literature:

With sodium hydroxide; sulfuric acid; bromine;

DOI:10.1002/prac.19923340214

Reference yield:

→ 2-bromo-5-ethylpyridine (19842-08-1) + 5,5'-diethyl-2,2'-bipyridyl (1762-43-2)

Guidance literature:

Reference yield:

→ 2-bromo-5-ethylpyridine (19842-08-1)

Guidance literature:

6-Amino-3-ethylpyridine, Br2;

DOI:10.1007/BF00474882

upstream raw materials:

3-ethylpyridine

Downstream raw materials:

tert-Butyl (6R)-6-{[5-(5-ethylpyridin-2-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]oxy}heptanoate

(3-{[5-(5-Ethylpyridin-2-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxy)acetic acid

Pioglitazone

methyl (3-{[5-(5-ethylpyridin-2-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxy)acetate