198471-06-6

Basic information

• Product Name: N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetaMide
• Synonyms: N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetaMide;AcetaMide, N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-;Parecoxib Sodium Impurity I;N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]acetamide;Parecoxib Impurity 10
• CAS NO: 198471-06-6
• Molecular Formula: C₁₈H₁₆N₂O₄S
• Molecular Weight: 356.39564
• Mol File: 198471-06-6.mol

Chemical Properties

• Appearance: /
• Density: 1.288±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 5.10±0.10(Predicted)
• CAS DataBase Reference: N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetaMide(198471-06-6)
• EPA Substance Registry System: N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetaMide(198471-06-6)

Safety Data

• Hazardous Substances Data: 198471-06-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetamide is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a versatile building block for the development of new drugs with potential therapeutic applications.
Used in Microbial Biotransformations:
N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)acetamide is employed in the microbial biotransformations of valdecoxib using microbial cultures. This process is crucial for predicting mammalian drug metabolism, which helps in understanding the pharmacokinetics and pharmacodynamics of the drug, ultimately contributing to the drug development process.

Upstream product

• 108-24-7 acetic anhydride 
• 181695-72-7 valdecoxib 

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