The present invention provides BACE inhibitors of Formula I: methods for their use, intermediates, and methods for their preparation.
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Page/Page column 13
(2011/02/15)
Facile generation of a strained cyclic vinyl cation by thermal solvolysis of cyclopent-1-enyl-λ3-bromanes
Last of the cyclic vinyl cations: The simple solvolysis of cyclopent-1 -enyl-13-bromane efficiently generates the highly strained cyclopent-1 -enyl cation at room temperature (see scheme). The very high nucleofugality of the aryl-13-bromanyl groups are re
Miyamoto, Kazunori,Shiro, Motoo,Ochiai, Masahito
supporting information; experimental part
p. 8931 - 8934
(2010/02/28)
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