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4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine is a pyrimidine-based organic compound, characterized by its chloro, methyl, and fluoro substituents, as well as its pyrimidine and aniline moieties. It is a white to off-white solid with a molecular formula of C14H13ClF2N4 and a molecular weight of 300.7 g/mol. 4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine is recognized for its potential as an antiviral and antitumor agent and is widely utilized in the pharmaceutical industry as a building block for the synthesis of various drugs and active pharmaceutical ingredients.

199463-20-2

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199463-20-2 Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine is used as a building block for the synthesis of various drugs and active pharmaceutical ingredients. Its unique structure and functional groups make it a valuable component in the development of new medications.
Used in Antiviral Applications:
4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine is used as an antiviral agent, leveraging its potential to inhibit viral replication and reduce the severity of viral infections. Its antiviral properties make it a promising candidate for the development of treatments for various viral diseases.
Used in Antitumor Applications:
4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine is used as an antitumor agent, exhibiting potential to inhibit the growth and proliferation of cancer cells. Its antitumor activity makes it a valuable compound in the development of cancer therapeutics.
Used in Chemical Reactions:
4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine is used as a reagent in chemical reactions to produce pharmaceuticals for the treatment of various diseases. Its versatility and reactivity in chemical processes contribute to the synthesis of a wide range of therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 199463-20-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,4,6 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 199463-20:
(8*1)+(7*9)+(6*9)+(5*4)+(4*6)+(3*3)+(2*2)+(1*0)=182
182 % 10 = 2
So 199463-20-2 is a valid CAS Registry Number.
InChI:InChI=1S/C12H11ClFN3/c1-7-8(2)15-12(17-11(7)13)16-10-5-3-9(14)4-6-10/h3-6H,1-2H3,(H,15,16,17)

199463-20-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine

1.2 Other means of identification

Product number -
Other names 4-Chloro-5,6-dimethyl-2-(4-fluorophenylamino)pyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:199463-20-2 SDS

199463-20-2Upstream product

199463-20-2Relevant articles and documents

Method for preparing revaprzan hydrochloride

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Paragraph 0056; 0057; 0058, (2018/03/24)

The invention discloses a method for preparing revaprzan hydrochloride (namely revaprazan). According to the method, a phase transfer catalyst is adopted for substitution reactions of key steps, waterand/or a low melting point organic solvent is adopted a

PREPARATION METHOD FOR REVAPRAZAN HYDROCHLORIDE

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Paragraph 0055; 0060; 0061; 0067; 0073; 0079; 0085; 0091, (2017/09/30)

Provided is a preparation method for revaprazan hydrochloride, the method comprising: (1) the preparation of 4-hydroxyl-2-(4-fluoroaniline)-5,6-dimethylpyrimidine; (2) the preparation of 4-chloro-2-(4-fluoroaniline)-5,6-dimethylpyrimidine; (3) the preparation of revaprazan hydrochloride. The method has advantages such as simple operations, high product purity, good yield and suitability for industrial production.

Revaprazan hydrochloride impurities and preparation method thereof

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Paragraph 0074-0075; 0076-0077; 0078-0079; 0080-0081, (2017/09/01)

The invention provides a compound with a structural formula X as shown in the specification, or a tautomer, mesomer, raceme, enantiomer, diastereomer or mixture thereof, or a pharmaceutically acceptable salt or solvate of the compound with the structural

Process for preparation of pyrimidine derivatives

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, (2008/06/13)

The present invention relates to a process for preparation of 5,6-dimethyl-2-(4-fluorophenyl-amino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine represented by the following formula (I), STR1 and its acid addition salts by reacting a pyrimidi

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