199611-76-2Relevant articles and documents
Noncanonical cation-π cyclizations of alkylidene β-ketoesters: Synthesis of spiro-fused and bridged bicyclic ring systems
Parsons, Dylan E.,Frontier, Alison J.
, p. 2008 - 2012 (2019/03/26)
Three cation-π cyclization cascades initiated at alkylidene β-ketoesters bearing pendent alkenes are described. Depending upon the alkene substitution pattern and the reaction conditions employed, it is possible to achieve selective synthesis of the three different types of products, including 1-halo-3-carbomethoxycyclohexanes, spiro-fused tricyclic systems, and [4.3.1] bridged bicyclic ring systems. All three reactions begin with 6-endo addition of an olefin to the alkylidene β-ketoester electrophile, followed by one of three different cation capture events.
Protocol for the synthesis of heteroaromatic ring-Fused cyclohexanones
Phun, Lien H.,Patil, Dadasaheb V.,Cavitt, Marchello A.,France, Stefan
supporting information; scheme or table, p. 1952 - 1955 (2011/06/25)
A general protocol for the catalytic homo-Nazarov cyclization of cyclopropyl heteroaryl ketones has been developed,which employs indiumtriflate as the promoter. A range of heteroaromatic ring-fused cyclohexanones was synthesized in 56-91% yield using this
