200937-21-9

Basic information

• Product Name: Boc-DL-Leu-OH H2o
• Synonyms: N-[(1,1-Dinethylethoxy)carbonyl]-leucine Monohydrate;N-[(1,1-Dimethylethoxy)carbonyl]leucine monohydrate;(RS)-Boc-2-amino-4-methyl-pentanoic acid hydrate;Boc-DL-leucine hydrate99%;(Tert-Butoxy)Carbonyl DL-Leu-OH·H2O
• CAS NO: 200937-21-9
• Molecular Formula: C11H23NO5
• Molecular Weight: 249.30402
• Mol File: 200937-21-9.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Store at RT.
• CAS DataBase Reference: Boc-DL-Leu-OH H2o(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-DL-Leu-OH H2o(200937-21-9)
• EPA Substance Registry System: Boc-DL-Leu-OH H2o(200937-21-9)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 200937-21-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Boc-DL-Leu-OH H2o is used as a building block in peptide synthesis for the development of peptide-based drugs and compounds. The Boc protecting group allows for the selective modification of the molecule, facilitating the creation of complex peptide structures with specific therapeutic properties.
Used in Research:
In the research field, Boc-DL-Leu-OH H2o is employed for the study and development of novel peptide sequences and their potential applications. Boc-DL-Leu-OH H2o's role in peptide synthesis aids researchers in exploring the structure-function relationships of peptides and proteins, contributing to advancements in biotechnology and medicine.

Downstream Products

• 129603-01-6 (R)-N^α-(tert-butoxycarbonyl)-N-methoxy-N-methylleucinamide 
• 129603-19-6 (S)-2-methyl-4-aminononane hydrochloride 
• 87694-50-6 N-(tert-butoxycarbonyl)-L-leucine-N'-methoxy-N'-methylamide 
• 58521-45-2 tert-butoxycarbonyl-L-leucinal 
• 129603-18-5 (R)-2-methyl-4-aminononane hydrochloride 
• 84863-67-2 (S)-t-butyl 1-(isopentylamino)-4-methyl-1-oxopentan-2-ylcarbamate 
• 248922-15-8 (S)-2-amino-1-{4-[bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-4-methyl-pentan-1-one 
• 248921-97-3 (S)-(1-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-ylmethyl}-3-methyl-butyl)-carbamic acid tert-butyl ester 
• 248922-25-0 (S)-2-Benzylamino-1-{4-[bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-4-methyl-pentan-1-one 
• 248922-20-5 (S)-1-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-2-(4-tert-butyl-benzylamino)-4-methyl-pentan-1-one 
• 248922-27-2 (S)-1-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-2-(4-tert-butoxy-benzylamino)-4-methyl-pentan-1-one 
• 248922-23-8 (S)-1-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-4-methyl-2-(3,4,5-trimethoxy-benzylamino)-pentan-1-one 
• 248922-21-6 (S)-2-[Bis-(4-tert-butyl-benzyl)-amino]-1-{4-[bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-4-methyl-pentan-1-one 
• 248922-19-2 (S)-2-[Bis-(4-tert-butoxy-benzyl)-amino]-1-{4-[bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}4-methyl-pentan-1-one 

Relevant articles and documents

Tumor metastasis inhibiting compounds and methods

A peptide derivative containing 1 to 20 units of peptide unit represented by the following general formula [I] or a pharmaceutically acceptable salt thereof; wherein Arg represents L- or D-arginine residue, Asp represents L-aspartic acid residue, X represents L- or D-leucine, D-isoleucine, L- or D-norleucine, L- or D-phenylalanine, D-phenylglycine or D-alanine residue, and [Z] and [Y] each represents an amino acid or a peptide residue, which may be present or absent, selected from glycine, L-serine, L-threonine, L- and D-aspartic acid, L-alanine, L- and D-glutamic acid, L-proline residues and a peptide residue constituted by the foregoing amino acid residues, and a pharmaceutical composition comprising the peptide derivative. The composition of the present invention is useful as an agent for inhibiting tumor metastasis.

Use of 2-pyrimidine thiol carbonates as acylating agents for amino or imino containing compounds

Thiolcarbonates represented by the formula, SPC1 Wherein R1 and R2 are individually a hydrogen atom or a methyl group, and R3 is a straight chain or branched chain saturated or unsaturated alkyl group having 1 to 5 carbon atoms or is a benzyl or benzhydryl group which may be nuclear substituted, are quite useful for protecting the amino or imino groups of amines, hydrazines, amino acids and peptides with groups of the formula EQU1 The thiolcarbonates can be easily produced by reacting an alkali metal salt of 2-mercaptopyrimidine with phosgene, and reacting the resulting thiolchloroformate with an alcohol (R3 OH), or by reacting a 2-mercaptopyrimidine with a halocarbonic acid ester.