201048-68-2 Usage
Uses
Used in Pharmaceutical Industry:
Z-ORN(FMOC)-OH is used as a building block in peptide synthesis for the development of therapeutic peptides. Its role in protecting the functional groups of ornithine during the synthesis process ensures the accurate formation of peptide sequences, which can be crucial for the biological activity and efficacy of the resulting peptides.
Used in Research and Development:
In the field of peptide chemistry research, Z-ORN(FMOC)-OH is utilized as a component in the synthesis of novel peptides with potential applications in various areas, such as drug discovery, diagnostics, and therapeutics. Its protective groups allow for the controlled assembly of peptide sequences, facilitating the exploration of new peptide-based compounds and their properties.
Used in Peptide Synthesis Education:
Z-ORN(FMOC)-OH serves as an educational tool in teaching the principles of peptide synthesis, including the use of protecting groups and the stepwise assembly of peptide chains. By incorporating Z-ORN(FMOC)-OH into laboratory exercises and coursework, students can gain hands-on experience in synthesizing peptides and understanding the importance of protecting groups in the process.
Check Digit Verification of cas no
The CAS Registry Mumber 201048-68-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,0,4 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 201048-68:
(8*2)+(7*0)+(6*1)+(5*0)+(4*4)+(3*8)+(2*6)+(1*8)=82
82 % 10 = 2
So 201048-68-2 is a valid CAS Registry Number.
201048-68-2Relevant articles and documents
MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
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Paragraph 001062, (2018/09/12)
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
Synthesis and evaluation of novel dipeptide-bound 1,2,4-thiadiazoles as irreversible inhibitors of guinea pig liver transglutaminase.
Marrano,de Macedo,Gagnon,Lapierre,Gravel,Keillor
, p. 3231 - 3241 (2007/10/03)
Herein we report the synthesis and evaluation of 14 novel peptides as potential irreversible inactivators of guinea pig liver transglutaminase (TGase). These peptides were designed to resemble Cbz-L-Gln-Gly, known to be a good TGase substrate, and to include a 1,2,4-thiadiazole group. The side chain length of the amino acid residue bearing the inhibitor group was also varied in order to permit investigation of this effect. Their inactivation rate constants were measured using a direct continuous spectrophotometric method and were found to vary between 0.330 to 0.89 microM(-1) min(-1).
