202057-76-9Relevant articles and documents
PROCESS FOR PRODUCTION OF 2-CYANO-3-HYDROXY-N-(4-TRI- FLUOROMETHYLPHENYL)HEPT-2-EN-6-YNAMIDE AND PROCESS FOR PRODUCTION OF POLYMORPHS THEREOF
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Page/Page column 5; 9-10, (2010/02/15)
A compound (II) is reacted with a compound (III) or a reactive derivative at the carboxyl group thereof to obtain a compound (IV), which is reacted with a mixed acid anhydride of a compound (V) to prepare a compound (I). In recrystallization of the compou
2-cyano-3-hydroxy-enamides
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, (2008/06/13)
A compound selected from the group consisting of a compound of the formula STR1 wherein R1 is selected from the group consisting of STR2 R13, R14 and R15 are individually selected from the group consisting of hydrogen, halogen and alkyl of 1 to 3 carbon atoms, n is an integer from 1 to 3, R2 is hydrogen or alkyl of 1 to 3 carbon atoms, R3, R4 R5, R6 and R7 are individually selected from the group consisting of hydrogen, halogen, --NO2, --CN, alkyl, alkylthio and alkoxy of 1 to 6 carbon atoms, alkylcarbonyl of 2 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, STR3 m is 0, 1, 2 or 3, n is 1, 2 or 3; Hal, Hal1, Hal2 and Hal3 are individually halogen and STR4 R8, R9, R10, R11 and R12 are individually any of the groups defined above for R3, R4, R5, R6 and R7 or R4 and R5 together form --O--CH2 --O-- and their non-toxic, pharmaceutically acceptable base addition salts having anti-inflammatory activity.
