202865-71-2

Basic information

• Product Name: 5-BROMO-2-FLUOROCINNAMIC ACID
• Synonyms: 2-Propenoic acid,3-(5-broMo-2-fluorophenyl)-;(E)-3-(5-broMo-2-fluorophenyl)acrylic acid;(2E)-3-(5-BROMO-2-FLUOROPHENYL)-2-PROPENOIC ACID;5-BROMO-2-FLUOROCINNAMIC ACID;3-(5-BROMO-2-FLUOROPHENYL)-2-PROPENOIC ACID;3-(5-BROMO-2-FLUORO-PHENYL)-ACRYLIC ACID;RARECHEM BK HW 0189;TIMTEC-BB SBB006748
• CAS NO: 202865-71-2
• Molecular Formula: C₉H₆BrFO₂
• Molecular Weight: 245.05
• Product Categories: Organic Building Blocks;Fluoro-contained cinnamic acid series;Aromatic Cinnamic Acids, Esters and Derivatives;Cinnamic acid;Acids & Esters;Bromine Compounds;Fluorine Compounds;Building Blocks;C9;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis
• Mol File: 202865-71-2.mol

Chemical Properties

• Melting Point: 195-199 °C
• Boiling Point: 335.958 °C at 760 mmHg
• Flash Point: 156.982 °C
• Appearance: white to light yellow crystal powder
• Density: 1.6228 (rough estimate)
• Vapor Pressure: 4.55E-05mmHg at 25°C
• Refractive Index: 1.4240 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.14±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2-FLUOROCINNAMIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-FLUOROCINNAMIC ACID(202865-71-2)
• EPA Substance Registry System: 5-BROMO-2-FLUOROCINNAMIC ACID(202865-71-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 202865-71-2(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powder

InChI:InChI=1/C9H6BrFO2/c10-7-2-3-8(11)6(5-7)1-4-9(12)13/h1-5H,(H,12,13)/p-1/b4-1+

Upstream product

• 141-82-2 malonic acid 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 

Downstream Products

• 1350816-53-3 3-(5-bromo-2-fluorophenyl)-N,N-dimethylpropan-1-amine 
• 1350816-54-4 9-chloro-2-({3-[3-(dimethylamino)propyl]-4-fluorophenyl}amino)-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-one 
• 1350816-15-7 9-chloro-2-({3-[3-(dimethylamino)propyl]-4-fluorophenyl}amino)-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepine-6-thione 

Relevant articles and documents

4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVE OR SALTS THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention provides a 4,5-dihydro-1H-pyrazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The 4,5-dihydro-1H-pyrazole derivative or its pharmaceutically acceptable salt effectively increases the LXR transcriptional activity, and therefore can be usefully applied for preventing or treating a dysfunction in cholesterol metabolism, such as cholesterol gallstone, hyperlipidemia, or coronary atherosclerosis.