cas 20295-34-5, Cyclopropanecarbothioamide

Articles about 20295-34-5Total 12 be found

Preparation of primary thioamides from nitriles using sodium hydrogen sulfide and diethylamine hydrochloride
Primary thioamides are prepared in moderate to excellent yields by treating nitriles with sodium hydrogen sulfide and diethylamine hydrochloride in an appropriate solvent with mild heating. Copyright Taylor & Francis LLC.
Boys, Mark L.,Downs, Victoria L.
p. 295 - 298
(2006)
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SUBSTITUTED THIAZOLE OR OXAZOLE P2X7 RECEPTOR ANTAGONISTS
The present invention refers to novel substituted thiazole and oxazole compounds of formula (I) having P2X7 receptor (P2X7) antagonistic properties. The compounds are useful in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans.
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Page/Page column 37

(2015/09/22)

Domino aryne precursor: Efficient construction of 2,4-disubstituted benzothiazoles
An aryne precursor with a potential to perform domino aryne chemistry was proposed and synthesized. The reaction of this reagent with benzothioamide derivatives could afford 2,4-disubstituted benzothiazole with sequential incorporation of C-S, C-N, and C-C bonds on the consecutive three positions of the aryne precursor.
Shi, Jiarong,Qiu, Dachuan,Wang, Juan,Xu, Hai,Li, Yang
supporting information
p. 5670 - 5673
(2015/05/20)

2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES
The invention relates to 2-aza-bicyclo[3.3.0]octane derivatives of Formula (I) wherein A, B, and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.
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Page/Page column 13

(2011/02/15)

2-CYCLOPROPYL-THIAZOLE DERIVATIVES
The invention relates to selected 2-cyclopropyl-thiazole derivatives of the formula (I) wherein B, Y and R1 are as described in the description; to salts and especially pharmaceutically acceptable salts thereof, and to the use of such compounds use as med
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Page/Page column 12; 22

(2010/09/07)

MODULATORS OF CXCR7
Compounds having formula (I) or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present inven
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Page/Page column 65

(2010/06/11)

PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES
The invention relates to novel phenethylamide derivatives and their heterocyclic analogues of formula (I), wherein A, B, R1, R2 and R3 are as described in the application, and to the use of such compounds, or of pharmaceut
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Page/Page column 85

(2010/04/30)

TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES
The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.
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Page/Page column 56

(2009/03/07)

2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES
The invention relates to 2-aza-bicyclo[3.3.0]octane derivatives of Formula (I) wherein A, B, and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.
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Page/Page column 26

(2009/03/07)

2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES
The invention relates to novel 2-aza-bicyclo[2.2.1]heptane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as m
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Page/Page column 43-44

(2009/10/18)

2-CYCLOPROPYL-THIAZOLE DERIVATIVES
The invention relates to selected 2-cyclopropyl-thiazole derivatives of the formula (I) wherein B, Y and R1 are as described in the description; to salts and especially pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.
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Page/Page column 44

(2009/01/20)

2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES
The invention relates to novel 2-aza-bicyclo[3.1.0]hexane derivatives of Formula (I) wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.
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Page/Page column 52-53

(2008/12/07)