- A High-Yield and Cost-Effective Synthesis of Spirotetramat
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Abstract: cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione, the key intermediate in the synthesis of spirotetramat, was synthesized by catalytic hydrogenation, oxidation, and Bucherer–Bergs reaction with 4-methoxycyclohexan-1-one as raw material. Spirotetramat was obtained in an overall yield of 20.4% by a multi-step reaction sequence including hydrolysis, esterification, acylation, intramolecular condensation, and O-acylation. The advantages of the proposed method are mild conditions, simple operation, and good to excellent yields in each step.
- Mao, Longfei,Wang, Jiahao,Xu, Guiqing,Zhou, Yingjie
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p. 1775 - 1778
(2020/12/01)
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- PROCESS FOR PREPARING CIS-ALKOXY-SUBSTITUTED SPIROCYCLIC PHENYLACETYLAMINO ACID ESTERS AND CIS- ALKOXY-SUBSTITUTED SPIROCYCLIC 1H- PYRROLIDINE-2,4-DIONE DERIVATIVES
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The present invention relates to a novel process for preparing cis-alkoxy-substituted spirocyclic phenylacetylamino acid esters and cis-alkoxy-substituted spirocyclic 1H-pyrrolidine-2,4-dione derivatives, and also to novel intermediates and starting materials which are produced and/or used in the process according to the invention.
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Paragraph 0079
(2015/02/25)
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- CIS-ALKOXY-SUBSTITUTED SPIROCYCLIC 1-H-PYRROLIDINE-2,4-DIONE DERIVATIVES SERVING AS PESTICIDES
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The invention relates to novel cis-alkoxy-substituted spirocyclic 1-H-pyrrolidine-2,4-dione derivatives of formula (I), in which A, G, X and Y have the meanings as cited in the description, to a number of methods for producing these derivatives and to the
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Page/Page column 87-88
(2008/06/13)
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