387825-55-0Relevant articles and documents
A High-Yield and Cost-Effective Synthesis of Spirotetramat
Mao, Longfei,Wang, Jiahao,Xu, Guiqing,Zhou, Yingjie
, p. 1775 - 1778 (2020/12/01)
Abstract: cis-8-Methoxy-1,3-diazaspiro[4.5]decane-2,4-dione, the key intermediate in the synthesis of spirotetramat, was synthesized by catalytic hydrogenation, oxidation, and Bucherer–Bergs reaction with 4-methoxycyclohexan-1-one as raw material. Spirotetramat was obtained in an overall yield of 20.4% by a multi-step reaction sequence including hydrolysis, esterification, acylation, intramolecular condensation, and O-acylation. The advantages of the proposed method are mild conditions, simple operation, and good to excellent yields in each step.
Preparation method of cis-isomer of 1-amino-4-substituted cyclohexyl carboxylic acid and salt thereof
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Paragraph 0034-0035, (2020/09/09)
The invention discloses a preparation method of cis-isomers of 1-amino-4-substituted cyclohexylcarboxylic acid and salt thereof, and belongs to the technical field of synthesis of medicines, pesticides and intermediates thereof. The method comprises the steps that: in a reaction solvent, a compound II reacts with cyanide and ammonium salt, so that a compound III can be obtained; the compound III is hydrolyzed under an alkaline condition, so that a compound I can be obtained; and the compound I and the compound III are both of a cis-structure. The process of the preparation method is simple; the ratio of the cis-isomer to trans-isomer of reaction products is greater than 90: 1 and 10, a splitting process of a cis/trans-isomer mixture is avoided, and therefore, an experiment process is greatly simplified, production time is shortened, at the same time, reaction raw materials can be saved, the product yield is improved, and the required solvent and catalyst are simple, easy to obtain, lowin price, high in raw material utilization rate and low in production cost.
Novel spirodecenol compound and preparation method thereof
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, (2018/05/16)
The invention discloses a novel spirodecenol compound and a preparation method thereof, and belongs to the technical field of pesticide synthesis. The invention adopts the key point that the novel spirodecenol compound has a structure as described in the specification. The invention also discloses a novel spirodecenol compound and a preparation method thereof. According to the invention, a novel spirodecenol compound is synthesized by a new method, a reaction process is simple and easy to operate, raw materials are cheap and easy to obtain, the reaction efficiency is high, the repeatability isgood, the insecticidal activity effect is obvious, and the spirodecenol compound has a good application prospect.
Novel triazole methyl ester compound and preparation method thereof
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Paragraph 0041; 0043, (2018/05/16)
The invention discloses a novel triazole methyl ester compound and a preparation method thereof, and belongs to the technical field of application chemistry. The invention adopts a key point that thenovel triazole methyl ester compound has a structure as described in the specification. The invention also discloses a novel triazole methyl ester compound and a preparation method thereof. Accordingto the invention, a novel triazole methyl ester compound is synthesized by a new method, a reaction process is simple and easy to operate, raw materials are cheap and easy to obtain, the reaction efficiency is high, the repeatability is good, and the insecticidal activity effect is obvious.
Novel preparation method of spirotetramat
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Paragraph 0030-0041, (2018/04/21)
The invention discloses a novel preparation method of spirotetramat and belongs to the technical field of pesticide syntyesis. The key point of the technical scheme is as follows: the method is characterized by carrying out cyclization reaction via 1-amin
Preparation method and application of novel aminoazaheterocycles compound
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Paragraph 0023; 0034; 0035; 0037, (2018/04/03)
The invention discloses a preparation method and application of a novel aminoazaheterocycles compound, and belongs to the technical field of applied chemistry. The technical scheme disclosed by the invention is characterized in that the novel aminoazaheterocycles compound has a following structure: a formula shown in the description. The invention further discloses the preparation method of the novel aminoazaheterocycles compound. The novel aminoazaheterocycles compound is synthesized through a new method; a reaction process is simple to operate and feasible, and raw materials are cheap and easy to obtain; the reaction efficiency is relatively high, and the repeatability is relatively good; the insecticidal activity effect is obvious.
