20342-64-7

Basic information

• Product Name: indole-4,7-dione
• Synonyms: indole-4,7-dione;indole-4,7-quinone
• CAS NO: 20342-64-7
• Molecular Formula: C₈H₅NO₂
• Molecular Weight: 147.13
• Mol File: 20342-64-7.mol

Chemical Properties

• Boiling Point: 369.3°Cat760mmHg
• Flash Point: 180.7°C
• Appearance: /
• Density: 1.458g/cm³
• Vapor Pressure: 1.2E-05mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: indole-4,7-dione(CAS DataBase Reference)
• NIST Chemistry Reference: indole-4,7-dione(20342-64-7)
• EPA Substance Registry System: indole-4,7-dione(20342-64-7)

Safety Data

• Hazardous Substances Data: 20342-64-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H5NO2/c10-6-1-2-7(11)8-5(6)3-4-9-8/h1-4,9H

Upstream product

• 144900-08-3 N-(trifluoroacetyl)-2-(2,5-dimethoxyanilino)acetaldehyde diethyl acetal 
• 538368-17-1 4,7-dimethoxy-indole-1-carboxylic acid tert-butyl ester 
• 23876-39-3 4,7-dimethoxylindole 
• 2380-94-1 1H-indol-4-ol 
• 538368-18-2 4,7-dioxo-4,7-dihydro-indole-1-carboxylic acid tert-butyl ester 
• 78942-75-3 4,7-dimethoxyindole-1-carboxylic acid ethyl ester 

Downstream Products

• 538368-20-6 N-[2-(4,9-dioxo-4,9-dihydro-1H-pyrrolo[3,2-g]quinolin-5-yl)-phenyl]-2,2,2-trifluoro-acetamide 

Relevant articles and documents

Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A

Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.

SUBSTITUTED QUINONE INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS AND SYNTHESES AND USES THEREFOR

The present invention relates to substituted mdoloqumone compounds of the general formula (A) and (B) and pharmaceutical compositions thereof that are inhibitors of mdoleamme-2,3-dioxygenase (IDO) More specifically, the invention relates to said compounds

Synthesis and antifungal activity of 1H-indole-4,7-diones

1H-Indole-4,7-diones were synthesized and tested for in vitro antifungal activity against fungi. The synthesized 1H-indole-4,7-diones generally showed good antifungal activity against Candida krusei, Cryptococcus neoformans, and Aspergillus niger. The results suggest that 1H-indole-4,7-diones would be potent antifungal agents.

Total synthesis of the marine pyridoacridine alkaloid sebastianine A

The synthesis of the marine alkaloid sebastianine A and of a regioisomer has been accomplished via hetero-Diels-Alder reaction of indole-4,7-dione or N-tosylindole-4,7-dione with trifluoroacetamidocinnamaldehyde dimethylhydrazone, and subsequent cyclisati

GENERAL SYNTHESIS OF 2,3-SUBSTITUTED 5-MEMBERED HETEROCYCLIC QUINONES

4,7-dimethoxybenzofuran, -thiophene, -selenophene and 4,7-dimethoxyindole have been prepared by a two-step procedure involving a cyclization-dehydration of the acetals (1).The oxidative demethylation of 4,7-dimethoxybenzothiophene, -selenophene and