204930-37-0

Basic information

• Product Name: 5-BROMO-1,3-DICHLORO-2-METHYLBENZENE
• Synonyms: 5-BROMO-1,3-DICHLORO-2-METHYLBENZENE;Benzene, 5-broMo-1,3-dichloro-2-Methyl-
• CAS NO: 204930-37-0
• Molecular Formula: C₇H₅BrCl₂
• Molecular Weight: 239.92
• Mol File: 204930-37-0.mol

Chemical Properties

• Boiling Point: 253.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.645±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-BROMO-1,3-DICHLORO-2-METHYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-1,3-DICHLORO-2-METHYLBENZENE(204930-37-0)
• EPA Substance Registry System: 5-BROMO-1,3-DICHLORO-2-METHYLBENZENE(204930-37-0)

Safety Data

• Hazardous Substances Data: 204930-37-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-1,3-Dichloro-2-Methylbenzene is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be chemically modified to produce a range of medicinal compounds. Its unique halogenated structure allows for versatile chemical reactions, facilitating the creation of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Bromo-1,3-Dichloro-2-Methylbenzene serves as an intermediate in the production of various agrochemicals, including pesticides and herbicides. Its reactivity and stability contribute to the development of effective compounds designed to protect crops and enhance agricultural productivity.
Used as a Solvent or Reagent:
5-Bromo-1,3-Dichloro-2-Methylbenzene can also be employed as a solvent or reagent in chemical reactions due to its solubility in organic solvents and its capacity to participate in a variety of chemical processes. This makes it a valuable component in various industrial applications where specific chemical transformations are required.
Safety Precautions:
Given its hazardous nature, 5-Bromo-1,3-Dichloro-2-Methylbenzene should be handled with caution. It is essential to work in a well-ventilated area and use appropriate personal protective equipment to minimize health and environmental risks associated with this compound.

Upstream product

• 54730-35-7 3,5-dichloro-4-methylaniline 
• 99-99-0 1-methyl-4-nitrobenzene 
• 7149-69-1 1,3-dichloro-2-methyl-5-nitrobenzene 

Downstream Products

• 956123-16-3 2-(4-bromo-2,6-dichloro-benzyl)-2-aza-spiro[4.5]decan-1-one 
• 274671-77-1 4-bromo-2,6-dichlorobenzyl alcohol 
• 111829-72-2 4-bromo-2,6-dichlorobenzaldehyde 
• 274671-76-0 5-bromo-2-(bromomethyl)-1,3-dichlorobenzene 

Relevant articles and documents

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INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1

The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11β-HSD type 1 activity.

INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1

The present invention discloses novel compounds of Formula I: having 11 Beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11Beta-HSD type 1 activity. X-17377

Kinetic studies on the interactions of manganese-porphyrins with peracetic acid. Part 1. Epoxidation of alkenes and hydroxylation of aromatic rings

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Transition metal catalysed cross-coupling between benzylic halides and aryl nucleophiles. Synthesis of some toxicologically interesting tetrachlorobenzyltoluenes

The aryl-benzyl cross-coupling in the presence of copper-, nickel- and palladium-catalysts has been investigated with a number of chlorine- and methyl-substituted arylmetal compounds ArM (M = MgBr, ZnCl) and (substituted) benzylic halides ArCH2X. The results have been applied in the selective synthesis of some toxicologically interesting tetrachlorobenzyltoluenes.