7149-69-1

Basic information

• Product Name: 1,3-DICHLORO-2-METHYL-5-NITROBENZENE
• Synonyms: 1,3-DICHLORO-2-METHYL-5-NITROBENZENE;NSC 72321;3,5-Dichloro-4-methylnitrobenzene, 1,3-Dichloro-2-methyl-5-nitrobenzene
• CAS NO: 7149-69-1
• Molecular Formula: C₇H₅Cl₂NO₂
• Molecular Weight: 206.03
• Product Categories: Phenyls & Phenyl-Het;Halogen toluene;Phenyls & Phenyl-Het
• Mol File: 7149-69-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 62-65
• Boiling Point: 280℃
• Flash Point: 123℃
• Appearance: /
• Density: 1.456
• Vapor Pressure: 0.00674mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1,3-DICHLORO-2-METHYL-5-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DICHLORO-2-METHYL-5-NITROBENZENE(7149-69-1)
• EPA Substance Registry System: 1,3-DICHLORO-2-METHYL-5-NITROBENZENE(7149-69-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• Hazardous Substances Data: 7149-69-1(Hazardous Substances Data)

Usage

General Description

1,3-Dichloro-2-methyl-5-nitrobenzene is a complex organic compound that includes the functional groups of chlorine, methyl, and nitro attached to a benzene ring. It is part of the broad aromatic halides category of organic compounds, characterized specifically by the presence of halogen atoms connected to the aromatic ring of the molecule. The specific properties and uses of 1,3-dichloro-2-methyl-5-nitrobenzene can vary, but like many aromatic halides, it could potentially be used in a variety of chemical applications or reactions. Nevertheless, this is a theoretical compound, though the anticipated molecular formula would be C7H5Cl2NO2. As with other synthetic chemicals, care should be taken to prevent unwanted reactions, exposure, or environmental release.

InChI:InChI=1/C7H5Cl2NO2/c1-4-6(8)2-5(10(11)12)3-7(4)9/h2-3H,1H3

Upstream product

• 99-99-0 1-methyl-4-nitrobenzene 
• 19853-82-8 2,4-dichloro-3-methyl-6-nitro-aniline 
• 942069-73-0 2-(3,5-dichloro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 858006-25-4 2,6-dichloro-3,4-dinitro-toluene 
• 7782-50-5 chlorine 
• 7647-18-9 antimonypentachloride 
• 121-86-8 2-chloro-4-nitrotoluene 
• 7705-08-0 iron(III) chloride 

Downstream Products

• 1098619-73-8 2,6-dichloro-4-iodo-benzoic acid methyl ester 
• 1613730-12-3 methyl 4-amino-2,6-dichloro-3-((trimethylsilyl)ethynyl)benzoate 
• 1613730-11-2 methyl 4-amino-2,6-dichloro-3-iodobenzoate 
• 232275-49-9 methyl 4-amino-2,6-dichlorobenzoate 
• 1533424-51-9 4-(5-amino-1H-[1,2,4]triazol-3-ylamino)-2,6-dichloro-N-(3-methanesulfonylphenyl)benzamide 
• 1533425-63-6 C₁₇H₁₆Cl₂N₄O₃S₂ 
• 1533425-62-5 2,6-dichloro-4-isothiocyanato-N-(3-methanesulfonylphenyl)benzamide 
• 1533425-61-4 4-amino-2,6-dichloro-N-(3-methanesulfonylphenyl)benzamide 
• 1533425-60-3 2,6-dichloro-N-(3-methanesulfonylphenyl)-4-nitrobenzamide 
• 1533424-50-8 [4-(5-amino-1H-[1,2,4]triazol-3-ylamino)-2,6-dichlorophenyl]pyrrolidin-1-ylmethanone 
• 1533425-58-9 (2,6-dichloro-4-isothiocyanatophenyl)(pyrrolidin-1-yl)methanone 
• 1533425-57-8 (4-amino-2,6-dichlorophenyl)(pyrrolidin-1-yl)methanone 
• 1533425-56-7 (2,6-dichloro-4-nitrophenyl)(pyrrolidin-1-yl)methanone 
• 1533424-49-5 4-(5-amino-1H-[1,2,4]triazol-3-ylamino)-2,6-dichloro-N-phenylbenzamide 

Relevant articles and documents

NOVEL COMPOUNDS AND THEIR USES AS THYROID HORMONE RECEPTOR AGONISTS

A compound of formula (I) or (Ia), or a tautomer or a pharmaceutically acceptable salt thereof is provided. Compounds of formula (II) to (V), or a tautomer or a pharmaceutically acceptable salt thereof are also provided. These compounds and the pharmaceutical compositions containing them are useful for the treatment of diseases such as obesity, hyperlipidemia, hypercholesterolemia and diabetes and other related disorders and diseases, and may be useful for other diseases such as NASH, atherosclerosis, cardiovascular diseases, hypothyroidism, thyroid cancer and other disorders and diseases related thereto． (I), (Ia)

A convenient synthesis of a lymphocyte function-associated antigen-1 (LFA-1) antagonist of 'Compound 4'

The lymphocyte function-associated antigen-1 (LFA-1) antagonist of 'Compound 4' was synthesised by a convenient route using cheap, commercially available starting materials and catalysts under mild reaction conditions and by easily handled reactions. The total yield in the preparation of 'Compound 4' was more than 38% via Sonogashira coupling of an iodide and an alkyne, reduction of the alkyne catalysed by Raney nickel and later steps involving hydrolysis of an ester, condensation of an acid and an amine and a final hydrolysis of an ester.

Preparation of fluorous Yamaguchi reagents and evaluation of their reactivity in esterification

Fluorous Yamaguchi (FY) reagents bearing a perfluoroalkyl chain were prepared and employed in esterification reactions; the yields were similar to those obtained with the traditional Yamaguchi (TY) reagent. Fluorous benzoic acids derived from the FY reagents were separated easily after the reaction. GC analysis revealed that the initial rates of reaction with the FY reagents were higher than those with the TY reagent. The acidities of benzoic acids produced from the FY and TY reagents were predicted by DFT to be similar (1.20 and 0.96, respectively).