- Poly-2-oxazoline-derived polyurethanes: A versatile synthetic approach to renewable polyurethane thermosets
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2-Nonyl-2-oxazoline and 2-(9-decenyl)-2-oxazoline have been copolymerized in different proportions by cationic ring-opening polymerization to obtain a series of random linear copolymers with tailored molecular weight and double bond functionality in the side chains. Thiol-ene addition of 2-mercaptoethanol has been used to produce a set of polyoxazoline-polyols under mild conditions and with quantitative double bond transformation. The polyols obtained in this way were reacted with methylene-bis(phenylisocyanate) to yield a series of amorphous and semicrystalline polyurethane networks. The thermal stability and the thermomechanical properties of these thermosets have been studied and related with the structure of the parent polyols.
- Del Rio, Enrique,Lligadas, Gerard,Ronda, Juan Carlos,Galia, Marina,Cadiz, Virginia
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- Antimicrobial Preservative Compositions for Personal Care Products
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A personal product antimicrobial preservative composition for preservation of topical personal care formulations is provided and includes [A] one or more undecylenic acid derivatives depicted by Formula (I), [B] one or more octanoic acid derivatives depicted by Formula (II), and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two ‘liquid alcohol ethers’; wherein, each of the two components [A] and [B] is present in the range of 5 to 20% by weight and together [A] and [B] constitute 10 to 30% by weight and the ‘liquid alcohol ether’, component [C], is present 70 to 90% by weight of the total preservative composition. A method for preserving personal care product from microbial attack is provided containing an aqueous phase comprising three component composition from about 0.5 to 2.5% by weight of the total personal care formulation.
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Paragraph 0059
(2014/10/29)
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- ANTIMICROBIAL PRESERVATIVE COMPOSITIONS FOR PERSONAL CARE PRODUCTS
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A personal product antimicrobial preservative composition for preservation of topical personal care formulations is provided comprising [A] one or more undecylenic acid derivatives depicted by Formula (I), [B] one or more octanoic acid derivatives depicted by Formula (II), and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two ‘liquid alcohol ethers’; wherein, each of the two components [A] and [B] is present in the range of 5 to 20% by weight and together [A] and [B] constitute 10 to 30% by weight and the ‘liquid alcohol ether’, component [C], is present 70 to 90% by weight of the total preservative composition. A method for preserving personal care product from microbial attack is provided containing an aqueous phase comprising three component composition from about 0.5 to 2.5% by weight of the total personal care formulation.
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Paragraph 0070
(2013/05/08)
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- ANTIMICROBIAL PRESERVATIVE COMPOSITIONS FOR PERSONAL CARE PRODUCTS
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A personal product antimicrobial preservative composition for preservation of topical personal care formulations is provided comprising [A] one or more undecylenic acid derivatives depicted by Formula (I), [B] one or more octanoic acid derivatives depicted by Formula (II), and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two 'liquid alcohol ethers'; wherein, each of the two components [A] and [B] is present in the range of 5 to 20 % by weight and together [A] and [B] constitute 10 to 30 % by weight and the 'liquid alcohol ether', component [C], is present 70 to 90 % by weight of the total preservative composition. A method for preserving personal care product from microbial attack is provided containing an aqueous phase comprising three component composition from about 0.5 to 2.5 % by weight of the total personal care formulation.
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Page/Page column 18
(2013/06/06)
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- Synthesis and anticonvulsant activity of N-(2-hydroxyethyl)amide derivatives
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A series novel of N-(2-hydroxyethyl)amide derivatives was synthesized and screened for their anticonvulsant activities by the maximal electroshock (MES) test, and their neurotoxicity was evaluated by the rotarod test (Tox). The maximal electroshock test showed that N-(2-hydroxyethyl)decanamide 1g, N-(2-hydroxyethyl)palmitamide 1l, and N-(2-hydroxyeth-yl)stearamide 1n were found to show a better anticonvulsant activity and also had lower toxicity than the marked anti-epileptic drug valproate. In the anti-MES potency test, these compounds exhibited median effective doses (ED50) of 22.0, 23.3, 20.5 mg/kg, respectively, and median toxicity doses (TD50) of 599.8, >1000, >1000 mg/kg, respectively, resulting in a protective index (PI) of 27.5, >42.9, >48.8, respectively. This is a much better protective index than that of the marked anti-epileptic drug valproate (PI = 1.6). To further investigate the effects of the anticonvulsant activity in several different models, compounds 1g, 1l, and 1n were tested having evoked convulsions with chemical substances, including pentylenetetrazloe, isoniazide, 3-mercaptopropionic acid, bicuculline, thiosemicarbazide, and strychnine.
- Guan, Li-Ping,Zhao, Dong-Hai,Xiu, Jing-Hui,Sui, Xin,Piao, Hu-Ri,Quan, Zhe-Shan
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experimental part
p. 34 - 40
(2009/06/18)
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- PERFLUOROALKYL SUBSTITUTED ACRYLATE MONOMERS AND POLYMERS THEREOF
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Fluoroalkyl amidoalkyl alcohols of the formula (I) are disclosed and their corresponding (meth)acrylate esters. These fluoroalkyl amidoalkyl (meth)acrylate monomers can be copolymerized with a wide variety of conventional ethylenically unsaturated monomers. The resulting copolymers are useful as water, oil- and grease- proofing agents for paper, textiles and hard surfaces such as masonry and wood.
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Page/Page column 10
(2008/06/13)
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- Therapeutic use of mono and bicarboxylic acid amides active at the peripheral cannabinoid receptor
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The following description concerns a therapeutic method for the treatment of diseases connected with the modulation of the cannabinoid peripheral receptor, comprising administering amidic derivatives of mono and bicarboxylic acids with aminoalcohols or arninoethers selectively active on said receptor.
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