An expedient N-terminal attachment methodology for the solid phase peptide synthesis
A general and successful N-terminal attachment methodology is described that allows the solid phase synthesis of oligopeptides from activated N-hydroxysuccinimide esters and amino acid lithium salts. The results of studies with different coupling systems for amide bond formation are presented. The oligomers were synthesized on solid support using a carbamate linker with final TFA/CH2Cl2 cleavage. This methodology was also applied for the preparation of peptide-substituted amides and esters in high purities and excellent yields.
Li,Sung Tsai Lin,Jian Hsiu Yang
p. 1608 - 1612
(2007/10/03)
STUDIES OF BITTER PEPTIDES FROM CASEIN HYDROLYZATE - VII. BITTERNESS OF THE RETRO-BPIa (VAL-ILE-PHE-PRO-PRO-GLY-ARG) AND ITS FRAGMENTS.
To explain the bitter taste exhibited by BPIa (Arg-Gly-Pro-Pro-Phe-Ile-Val) which was isolated from casein hydrolyzate, the authors propose the following requirement: its characteristic spatial structure: the basic moiety in the N-terminal and the hydroph
Shigenaga,Otagiri,Kanehisa,Okai
p. 103 - 107
(2007/10/02)
Use of NN'-isopropylidene dipeptides in peptide synthesis.
-
Hardy,Samworth
p. 1954 - 1960
(2007/10/08)
More Articles about upstream products of 20556-14-3