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3-Pyridinemethanamine,2-fluoro-(9CI), with the molecular formula C6H7FN2 and CAS number 872557-68-9, is a pyridine derivative featuring a fluorine substituent. This chemical compound is widely recognized for its significance in medicinal chemistry and pharmaceutical research, serving as a versatile building block for the synthesis of a variety of organic compounds. Its unique properties and potential applications in organic synthesis and pharmaceutical research render it an essential component in the development of innovative drugs and biologically active compounds.

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  • 205744-16-7 Structure
  • Basic information

    1. Product Name: 3-Pyridinemethanamine,2-fluoro-(9CI)
    2. Synonyms: 3-Pyridinemethanamine,2-fluoro-(9CI);2-fluoro-3-(aminomethyl)pyridine
    3. CAS NO:205744-16-7
    4. Molecular Formula: C6H7FN2
    5. Molecular Weight: 126.1315832
    6. EINECS: N/A
    7. Product Categories: PYRIDINE
    8. Mol File: 205744-16-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 225.6 °C at 760 mmHg
    3. Flash Point: 90.2 °C
    4. Appearance: /
    5. Density: 1.18 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C(protect from light)
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-Pyridinemethanamine,2-fluoro-(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-Pyridinemethanamine,2-fluoro-(9CI)(205744-16-7)
    11. EPA Substance Registry System: 3-Pyridinemethanamine,2-fluoro-(9CI)(205744-16-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 205744-16-7(Hazardous Substances Data)

205744-16-7 Usage

Uses

Used in Pharmaceutical Research and Development:
3-Pyridinemethanamine,2-fluoro-(9CI) is utilized as a key intermediate in the synthesis of pharmaceutical compounds for various therapeutic applications. Its presence in the molecular structure of target compounds can influence their pharmacokinetic and pharmacodynamic properties, enhancing their efficacy and safety profiles.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3-Pyridinemethanamine,2-fluoro-(9CI) is employed as a structural component in the design and synthesis of novel drug candidates. Its incorporation into molecular frameworks can impart specific biological activities, contributing to the discovery of new therapeutic agents with improved potency and selectivity.
Used in Drug Discovery:
3-Pyridinemethanamine,2-fluoro-(9CI) plays a crucial role in drug discovery, where it is used as a starting material or a building block for the development of new chemical entities. Its unique structural features and reactivity make it a valuable asset in the creation of diverse chemical libraries for high-throughput screening and lead optimization processes.
Used in Organic Synthesis:
Beyond its pharmaceutical applications, 3-Pyridinemethanamine,2-fluoro-(9CI) is also used in organic synthesis for the preparation of various organic compounds. Its reactivity and functional group compatibility make it a useful component in the synthesis of complex organic molecules, including natural products, agrochemicals, and specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 205744-16-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,7,4 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 205744-16:
(8*2)+(7*0)+(6*5)+(5*7)+(4*4)+(3*4)+(2*1)+(1*6)=117
117 % 10 = 7
So 205744-16-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H7FN2.HCL/c7-6-5(4-8)2-1-3-9-6/h1-3H,4,8H2

205744-16-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-fluoropyridin-3-yl)methanamine

1.2 Other means of identification

Product number -
Other names 3-aminomethyl-2-fluoropyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:205744-16-7 SDS

205744-16-7Upstream product

205744-16-7Downstream Products

205744-16-7Relevant articles and documents

7-Substituted Purine Derivatives for Immunosuppression

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Page/Page column 10, (2008/12/05)

The present invention provides novel purinone and related derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formula III:

7-SUBSTITUTED PURINE DERIVATIVES FOR IMMUNOSUPPRESSION

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Page/Page column 30, (2008/12/05)

The present invention provides novel purinone and related derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formula (III).

PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION

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Page/Page column 31, (2010/11/24)

The present invention provides novel purine and imidazopyridine derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formulas ( I ) and ( II ).

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