206268-17-9

Basic information

• Product Name: Carbamic acid, (4-amino-2-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (4-amino-2-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 206268-17-9
• Molecular Formula: C₉H₂₀N₂O₃
• Molecular Weight: 204.2667
• Product Categories: N-BOC
• Mol File: 206268-17-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, (4-amino-2-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (4-amino-2-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)(206268-17-9)
• EPA Substance Registry System: Carbamic acid, (4-amino-2-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)(206268-17-9)

Safety Data

• Hazardous Substances Data: 206268-17-9(Hazardous Substances Data)

Upstream product

• 206268-12-4 Isoxazolidin-5-ylmethyl-carbamic acid tert-butyl ester 
• 206268-14-6 2-benzyl-5-tert-butyloxycarbonylaminomethyl-(1,2)-isoxazolidine 
• 78888-18-3 N-tert-butoxycarbonylprop-2-en-1-amine 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

PYRAZOLO-TRIAZINE AND/OR PYRAZOLO-PYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITOR OF CYCLIN DEPENDENT KINASE

The present invention relates to pyrazolo[1,5-a][1,3,5]triazine and pyrazolo[l,5-a]pyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of cell proliferative diseases, inflammatory diseases, immunological diseases, cardiovascular diseases and infectious diseases. Furthermore, the present invention is directed towards pharmaceutical compositions containing at least one of the pyrazolo[1,5-a][1,3,5]triazine and pyrazolo[1,5-a]pyrimidine derivatives and/or pharmaceutically acceptable salts thereof.

Synthesis of perhydrodiazepinones as new putative peptidomimetics

New functionalized 7-membered azaheterocycles (perhydrodiazepinones) have been designed as new scaffolds supposed to mimick peptide γ-turns constrained by an ethylene bridge. They were synthesized by either lactam cyclisation on an aminoacid compound outcoming from a glutamic acid derivative starting material or through an intramolecular Mitsunobu reaction on diaminoalcohol linear precursors. Furthermore, as a new strategy useful for combinatorial chemistry, the second synthesis has been investigated on a soluble polymer support (PEG).

Synthesis of new perhydro-(1,4)-diazepin-2-ones as constrained peptidomimetics

New access to substituted perhydro-(1,4)-diazepin-2-ones has been developed through either a Mitsunobu reaction or an amide bond formation for the cyclisation key step.